Wilson-Konovalov disease: genetic disorder caused by ATP 78 gene mutation leading to dangerous copper accumulation. Symptoms appear in childhood/adulthood triggered by infections/trauma/copper exposure.

Excess is very dangerous.

Wilson-Konovalov disease is a genetic disorder caused by mutations in the ATP 78 gene located on chromosome 13. The first symptoms of the disease can appear both in childhood and in adults.

As a rule, the manifestation of the disease occurs about five years. In the future, during life, symptoms of excessive accumulation of copper in the body may appear. To date, the latest manifestation is registered at the age of 45 years.

The trigger for the appearance of the first symptoms can be infectious diseases, especially those caused by hepatotoxic viruses, traumatic brain injuries, and living in an area with a high content of copper in the environment, such as water, can also affect.