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Warning: Langya Virus – The Next Potential Global Health Emergency

Page “Center for Medical Genomics” or Center for Medical Genomics Faculty of Medicine Ramathibodi Hospital has posted a message Warning of a new strain of virus that will replace “Covid” which can be transmitted from animals to people. part states that “Is the world ready for the new virus after COVID? “Langya virus”, one of the members of the henipavirus family that may replace the COVID-19 virus. After August 2022, Langya virus (Langya, LayV), a new member of the henipa virus, was detected in a cohort of fever patients in eastern China.

Dr Ariel Isaacs and Dr Yu Chang Lowe, from the School of Chemistry and Molecular Biosciences at the University of Queensland, Australia, published their findings in the medical journal Nature Communications. ” this month (June 2023) indicates that there is a very high risk of the “Langya virus” in the less well-known Langya henipavirus (LayV,) group. There is going to be a massive epidemic in humans. although no human-to-human transmission has yet been found But instead, there was an increasing frequency of animal-to-human transmission of the Lungya virus and its members. And if only a few mutations in the genome cause the viral spines to bind better to human cells, it will allow the langya virus to transcend from animals to infect humans. The same happened with the 2019 coronavirus in the past.

The Medical Genome Center, Ramathibodi Hospital, has prepared mass array genotyping to detect the virus from the specimen. world health organization And scientists around the world predict that the next pandemic infectious disease threat to humanity beyond the COVID-19 virus. new strains or avian influenza viruses It could be the Hannipa virus group. These include Langya, Mòjiāng, Nipah and Hendra viruses, etc., which are classified in the family. Paramyxoviridae

Langya virus is a viral disease transmitted from animals to humans. It was first found in 35 farmers in China’s Shandong and Henan provinces. In 2022, it has been found to infect mammals such as humans, dogs, goats. It is believed that its original host is pets. small mammals resembling rodents Has a long, sharp mouth (shrews), but there are no reports of deaths due to the Langya virus, an emerging virus and it has not yet been found that the Langya virus can be transmitted from person to person.

Researchers warn that this is not the first time the Langya virus has spread to people. And it won’t be the last time. This virus is relatively new. (for humans) that could pose a global health emergency. And there are some worrying similarities with the coronavirus that has spread in humans around the world.

Dr. Ariel Isaacs and a team of researchers have discovered the structure of proteins on the virus’ spines known as spores. “Fusion proteins” The function of fusion proteins is to act as a bridge to carry the Langya virus into the cell. It fuses the viral sheath with the cell membrane of an infected person. This allows the virus to enter the cell and begin to multiply within the infectious cell. Using cryogenic electron microscopy at the University of Queensland Center for Microscopy and Virus Particle Analysis, the research team studied the structure of protein fusion at the atomic level. Australia

Now, the research team is working on the spike to use the information to develop a vaccine that can inject against all subtypes of the virus. (Broad-spectrum vaccine) as well as the development of antiviral drugs to treat viral infections of the Langya, Mojiang, Nipah, and Hendra families. Paramyxoviridae

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2023-06-30 07:49:56

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