Wednesday, August 16, 2023, 02:41
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A group of scientists led by Tokyo Medical University, Japanwho conducted an extensive study published in the journal Nature Scientific Reports on 9
August 2023, made an important health discovery. Experts have found that people with vitamin D deficiency are the most vulnerable to hip fractures.
Research has shown that supplementing vitamin D intake in people who are deficient helps prevent hip fractures, especially in older people, according to News Medical.
Osteoporosis, a chronic musculoskeletal condition, damages bone tissue and increases the risk of fracture. The osteoporotic population and subsequent fractures are expected to increase as the world’s population ages. Fragility fractures are common among patients with osteoporosis. In the elderly, fractures are linked to disability, poorer quality of life and a higher risk of refractoriness.
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Treatment for osteoporosis is essential for preventing fractures in the elderly. Vitamin D has been used as a medication for osteoporosis, and active forms of vitamin D have been reported to increase bone mineral density (BMD).
Vitamin supplementation has been shown to reduce the risk of vertebral and nonvertebral fractures, increase bone mass, and improve calcium regulation. In the present study, researchers in Japan evaluated the effects of vitamin D supplementation on fracture prevention using NDB data between March 2012 and March 2019.
The team analyzed data from osteoporotic individuals over the age of 40 who did not receive vitamin D for six months before the study began. Individuals were excluded from the analysis if they received non-osteoporosis medication at least once during the study period (between study entry and three years after study entry) or if they received medication for more than 90 days.
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In addition, people who developed osteoporosis-related fractures at the start of the study or within three months were excluded. Individuals were registered between September 2012 and March 2016.
Among participants, 422,454 untreated individuals never received vitamin D during follow-up, and 169,774 treated individuals had a medication possession ratio (MPR) of ≥ 0.50 for vitamin D at any time.
At follow-up, a total of 26,845 untreated individuals developed fractures, including 4,008 hip, 20,197 vertebral, and 2,640 radial fractures. The number of corresponding fractures among treated individuals was 687, 6,730, and 981, respectively.
The incidence of fractures was significantly lower among individuals who supplemented with vitamin D. After localization, hip fractures were significantly reduced, but not radial and vertebral fractures.
2023-08-15 22:16:04
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