Vitamin D deficiency increases the chances of obesity and fat accumulation

A research study conducted by researchers at the University of North Carolina State University in America revealed that Vitamin D deficiency It can lead to obesity, as researchers have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation. Using a zebrafish model, the study suggests, published in the journal Scientific Reports, A link between vitamin D and metabolic balance or homeostasis.

According to a newspaper report TIME NOW NEWS “Zebrafish, deficient in vitamin D, showed enlargement and an increase in the size and number of fat cells,” said study author Seth Coleman of North Carolina State University.

“They also have a higher percentage of triglycerides and cholesterol, which are hallmarks of a metabolic imbalance that can lead to heart disease and metabolism,” Coleman added. This, together with stunted growth, indicates that vitamin D plays an important role in the ability to Directing energy to growth versus storing fat.

For the study, the research team looked at groups of zebrafish after juveniles on one of three diets: no vitamin D (or free vitamin D), and vitamin D rich and controlled.

The zebrafish spent four months on their own diet, and then the researchers looked at their growth, bone density, triglycerides, fats, cholesterol, and vitamin D levels.

They also examined the main metabolic pathways associated with fat production, storage, packaging and growth promotion. The zebrafish in the vitamin D-deficient group were, on average, 50% smaller than those in the other two groups, and they had greater fat stores. .

After the initial test, the vitamin D deficient zebrafish were given a diet rich in vitamin D for an additional six months, to see if the results could be reversed. While the fish continued to grow and began to benefit from fat reserves, they did She joined the volume with the other groups and retained the remaining fat deposits.

“This work shows that vitamin D deficiency can affect metabolic health by disrupting the natural balance between growth and fat accumulation,” Coleman said.

The researchers pointed out that future work will include looking at the offspring of mothers who suffer from vitamin D deficiency, to determine whether this vitamin deficiency has genetic effects that can be transmitted.

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