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Universal flu vaccine could arrive in two years thanks to mRNA technology

A universal messenger RNA vaccine against all types of flu

Photo: Stephen Zenner (Getty Images)

A preclinical study published in Science brings us closer to a universal vaccine to protect humans from a potentially devastating flu pandemic. The mRNA vaccine encodes the antigens of all known influenza virus subtypes and has been shown to be effective in animal studies.

Now overshadowed by covid, the 2009 swine flu pandemic was an ominous reminder that a deadly strain of the flu virus it can spread rapidly around the world, as happened with the devastating Spanish flu of 1918. Scientists it’s been decades looking for a universal flu vaccine, but the long-awaited injection that protects us against all strains of the virus has been dodge. This could change in the coming years thanks to messenger RNA technology, which has already been used successfully against covid.

a vaccine of ARNO delivery courier for all kinds of flu

researchers of the The Perelman School of Medicine, at the University of Pennsylvania, has developed an experimental vaccine from mRNA which encodes antigens from all 20 known influenza A and B virus subtypes. In tests with mice and ferrets, this The vaccine generated high levels of antibodies that remained stable for several months, protecting the animals against all subtypes. from viruses simultaneously and potentially against unknown strains. While its efficacy and safety in humans have yet to be demonstrated, the study paves the way for clinical trials of the vaccine.what trust the researchers ready in less than two years.

Vaccines of seasonal flu, which protects against four viral strains at mostthey are updated every year to match with the virus in circulation. A universal vaccine (and this It’s not the only one in development) could prepare the immune system to deal with any kind of flu.

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