Understanding the Mechanism of Action of the Injectable Drug for Obesity: Insights from Dr. Cormillot

Dr. Cormillot indicates how the injectable drug for obesity works.

“Doctor, what is this weight loss vaccine?” people ask me. Well, it’s not a vaccine. Yes, it is an injection that is given in the same way as vaccines and that was approved a few weeks ago by the National Administration of Medicines, Food and Medical Technology (ANMAT).

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How is? It is a subcutaneous injection that is similar to a hormone produced by the intestine that helps control appetite and tells the brain when to stop eating.

The truth is that, despite the fact that now all the lights were put on this drug, first liraglutide appeared, which was a daily injection, it was used for diabetes and then it was seen that people lost weight and it began to be used for obesity.

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Then they said, “Well, we have to find one that lasts a little longer, because people don’t like getting punctures every day.” And semaglutide appeared, which is used subcutaneously once a week, as I told you, and regulates appetite for 7 days.

Have you failed many times? It doesn’t matter, you can always start again,” said Cormillot (iStock)

Semaglutide is an “analog” drug and is called that “because it is similar to something the body makes.” In this case, it is the hormone GLP1 that “is produced by the body when the person eats.”

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Can a person use semaglutide and do no treatment? Power may be possible, but it is not convenient for him because it is very possible that if he does not make a small change in habits, that person ends up relapsing into the issue, that is, he relies too much on that crutch.

Is it a strong crutch? It is very strong. It is the best thing that has been invented so far. New things will be invented, but today it is a medicine that is safe, effective and allows you to lose weight for a long time.

These drugs help regulate appetite, promote satiety, help control blood glucose levels and therefore improve the treatment of diabetes. In addition, it reduces the appetite for fats.

It is not a vaccine, but it is an injection that is administered like vaccines, opening a new chapter in treatments for obesity (iStock)

In which patients is it indicated? In those people who have at least 7 or 8 extra kilos, with some complication, whether hypertension or cholesterol. Or people who have 15 or 20 extra kilos, without any complications.

What contraindications does it have? It should not be used in patients with a history of thyroid cancer, or those who report having had diseases in several glands.

And what are the possible side effects? In most cases, they are digestive problems, some nausea, some complication of that type, but that does not make people stop the treatment, but rather one reduces the dose and waits, because it generally disappears.

It’s not magic. The truth is that, in addition to the correct application of the drug, to lose weight in a healthy way, diet and physical activity, stress management and better rest are required. Because if you don’t do the rest of the things, chances are it won’t work. When it comes to losing weight, the only magic there is is the precise moment when one stops looking for the magic to lose weight.

Have you failed many times? It doesn’t matter, you can always start over. Remember that today is the first day of the rest of your life.

*Dr. Alberto Cormillot is a renowned Argentine doctor, obesity specialist, health educator, writer and lecturer. He founded and directs the Nutrition and Health Clinic that bears his name, Dieta Club, the ALCO Foundation (Anonymous Fighters Against Obesity) and the Argentine Institute of Nutrition, from where he advises industries on the production of dietary products. and healthy.

2023-09-19 04:08:40
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