The Autobots and Decepticons once dueled on Earth, with the Transformers heroes getting a blood key upgrade from Wolverine. However, Optimus Prime and the other Autobots only resorted to Wolverine’s blood to retaliate against Megatron and his forces, who just so happen to be using Spider-Man’s blood to give themselves a boost. The Energized Transformers would fight as the Avengers aid Optimus Prime’s team.
New Avengers/Transformers from Marvel Comics by Stuart Moore, Tyler Kirkham, Sal Regla, Anette Kwok and Todd Klein featured the Decepticons attacking Earth with a structure called the Array – which launched a wave of energy that altered the minds of those nearby. To retaliate and stop a war between Latveria and a neighboring country over the Psycho-Prism, the Autobots and the Avengers teamed up to stop Megatron and his army. However, Megatron is even deadlier after taking a serum with Spider-Man’s blood. In response, Optimus Prime powers up with an upgrade using a serum from Wolverine’s blood.
In the crossover series, New Avengers/Transformers #4, Spider-Man breaks free from capture in The Array and joins the Avengers in an attempt to defeat Megatron. Iron Man releases his Anti-Transformer Armor, which matches Megatron’s size, but ultimately fails as the villain counters it with his new powers with an energy blast decapitating the suit. Spider-Man returns to the Transformers and offers his blood to create a serum to power the Autobots, but when Wolverine crashes the party, he suggests upgrading by taking his mutant blood. The Autobots thank Logan for potentially saving everyone, to which Logan replies, “peachy.”
Using Wolverine’s blood to enhance their powers would eventually help sway the battle in favor of the Autobot. Wolverine would take out the mind-altering device in the Array, as Optimus Prime, Luke Cage, and Spider-Man would defeat Megatron. Although it is hinted that the Autobots acquired Wolverine’s healing factor after taking the serum with his blood, the comic does not explicitly show that they are cured. However, given that it helped turn the tide against Megatron, there’s no doubt Wolverine’s blood made them stronger.
The blood of Spider-Man and Wolverine used to power the Decepticons and Autobots shows how heroes can be used as weapons in more ways than just their physical form. As weird as using Carcajous blood to feed Transformers was, he ended up being the missing ingredient to stop Megatron on Earth. It’s one of the more bizarre power upgrades, but it’s hard to argue how effective it is.
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