A study by the University of Birmingham suggests that sleep patterns and levels of stress hormones could play a key role in understanding when and how people with epilepsy may have seizures.
This research looked at how different physiological processes, such as sleep and variations in the concentration of the stress hormone cortisol, can influence the hallmarks of epilepsy known as epileptiform discharges (EDs).
Using 24-hour EEG recordings from 107 people with idiopathic generalized epilepsy, the researchers found two distinct subgroups with different distributions of EDs: one with a higher incidence of them during sleep and another during the day. The research revealed that cortisol dynamics, transitions during sleep, or a combination of both explained most of the observed distributions of ED.
Epilepsy is a serious neurological disorder characterized by a tendency to have recurrent spontaneous seizures, and this study sheds new light on how physiological processes can influence the timing of seizure onset.
These findings could contribute to a better understanding of the factors underlying seizures and the development of more effective treatments for epilepsy patients.
Source: 360medical.ro
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2023-10-21 10:41:27
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