The risks of fluoroquinolones have been known for some time. Therefore, the use of this type of antibiotics has been restricted in 2019. Although their use has decreased after these measures, doctors may still prescribe these drugs outside the restricted indication area, the PRAC indicates.
The monitoring committee therefore repeats the advice to using fluoroquinolones as last-line treatment after careful consideration of the benefits and risks and then only in patients for whom there are no alternative therapeutic options. Handlers they would should not apply in the following cases, among others:
- in mild to moderately severe bacterial infections, unless other antibiotics are not suitable;
- bee infections that do not require treatment for recovery;
- bee non-bacterial infections (such as non-bacterial prostatitis);
- bee traveler’s diarrhea and
- bee recurrent lower urinary tract infections.
Furthermore, special caution is advised in patients receiving concomitant corticosteroid therapy, in older adults, in patients with renal impairment and in patients who have undergone organ transplantation. In these patients there may be an increased risk of tendonitis and tendon rupture.
The group of fluoroquinolones includes ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin. These antibiotics have a broad spectrum of activity.
2023-05-15 12:30:26
#PRAC #warns #fluoroquinolones #Pharmaceutisch #Weekblad
