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The Protective Effects of Cardiorespiratory Fitness on Cancer Risk and Mortality in Men: A Study

Source: www.wikimedia.org

In the last year, multiple scientific studies have emphasized the benefits of sport and the protective effects of muscle mass on health, by reducing the risk of cardiometabolic conditions (insulin resistance, diabetes, obesity), but also neurodegenerative diseases (such as Alzheimer’s), bringing explanations up to the level molecular.

A new study, published in JAMA Network Openlinks the moderate to high level of cardiorespiratory fitness (cardiorespiratory capacity) of the reduced risk of occurrence and death due to the most common cancers in men – colon, lung, prostate.

Cardiorespiratory fitness (CRF) refers to the ability of the circulatory and respiratory systems to deliver oxygen to the skeletal muscles during sustained physical activity. CRF is used to assess the functional capacity of the cardiorespiratory system.

In a theoretical calculation, avoiding a very low cardiorespiratory level could have prevented 4% to 8% of all colon cancer cases, 4% of all lung cancer deaths, and 4% to 19% of all lung cancer deaths. prostate cancer.

The authors point out thatwhile physical activity and cardiorespiratory fitness are linked, physical activity is the behavior and the other is the physiological response.

“Historically, we have focused on the role of physical activity in reducing cancer risk, but the exciting finding from this large study is that cardiorespiratory fitness is also important in reducing a man’s risk of developing and dying due to certain types of cancer. (…) It is important for the general public to understand that [activitatea fizică] of high intensity has greater effects on [capacității cardiorespiratorii]which increases the protective character against the risk of developing and dying from certain types of cancer”.

The team studied the data a over 177 thousand Swedish men who completed workplace health profile assessments from October 1982 to December 2019 and compared these data with de novo cancer incidence and mortality data from national registries. The health profile assessment is an optional, free service offered in the Swedish healthcare system since the 1970s to all employees.

During a median follow-up of approximately 10 years, there were 499 cases of colon cancer, 283 of lung cancer, and 1,918 of prostate cancer; there were also 152 deaths from colon cancer, 207 from lung cancer and 141 from prostate cancer.

Higher cardiorespiratory capacity, as determined from maximal estimated oxygen consumption in a cycle ergometer exercise test, was associated with significantly lower risks of colon and lung cancer, although with a higher risk of prostate cancer. The latter result could be due to increased prostate cancer screening among fit men, the researchers suggest, or the important role that inherited factors play in this cancer. However, in the case of decreased risk of death, the association was maintained for all 3 types of cancer.

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2023-07-17 17:45:38
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