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The Potential of Natural Herbal Compounds in Improving Men’s Reproductive Health: Insights from Prof Dr Drs Yurnadi’s Scientific Oration

ruzka.republika.co.id–The Potential of Natural Herbal Compounds to Improve Men’s Reproductive Health in the Context of Creating Healthy Indonesian Human Resources. That was the scientific oration when Prof Dr Drs Yurnadi, M.Kes was inaugurated as Professor in the Field of Medical Biology, Faculty of Medicine (University of Indonesia (FKUI).

The inauguration procession was led directly by the Chancellor of UI, Prof. Ari Kuncoro, SE, MA, Ph.D held at the IMERI FKUI Salemba Hall, Jakarta, Saturday (14/10/2023).

In his speech, Prof. Yurnadi said that the prevalence of infertility in the world has increased in recent years. In 60-70 million married couples (couples), 40-70 percent of infertility is caused by the man.

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One of the main factors is hormonal disorders due to disturbances in the pituitary-hypothalamic-testicular axis in regulating gonadotropin hormone levels. This condition affects sperm formation so that sperm production and testosterone hormone levels decrease. As a result, a fertility disorder called hypogonadism arises.

To treat infertility problems such as hypogonadism, there are natural flora and fauna ingredients that have the potential to be used as medicine.

Natural ingredients have chemical diversity that is superior to synthetic ingredients because they contain secondary metabolites that provide pharmacological, therapeutic, antioxidant and antibacterial effects.

The natural ingredients that are useful for overcoming fertility problems in the male reproductive system are Javanese Chilies and Seahorses.

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Javanese chili plants (Piper retrofractum Vahl) are widely used for treatment. The fruit of this plant has been used to treat flatulence and heartburn, stimulate appetite, and overcome impotence.

The ingredients contained in this fruit have a stimulant effect on nerve cells so that they can increase the body’s stamina. The chemical compounds contained in Javanese chilies are alkaloids, β-sitosterol, terpenoids, saponins, resins (kavicin) and so on which can improve blood circulation.

Experimental research was carried out on mice induced with Depo Medroxy Progesterone Acetate (DMPA). The mice were given Javanese chili extract.

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As a result, Javanese chili extract can reduce sperm concentration and increase testosterone hormone levels, without affecting the hematological profile, blood chemistry and body weight of mice even though the experiment was carried out for 18 weeks.

2023-10-17 17:26:00
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