The new strain of COVID-19 mutated “Mo Yong” has evaded immunity from vaccines. Resulting in a decrease in the effectiveness of the vaccine
News reports state that Dr. Yongphu Worawan, MD. (Doctor YongHead of Center of Specialization in Clinical Virology Department of Pediatrics Faculty of Medicine Chulalongkorn University Has posted on facebook (Yong Poovorawan) Under the heading “COVID 19 mutations”
virusCOVID-19 It’s an RNA virus. Therefore has evolved to change genetics over time Therefore, mutations of the covid-19 virus are possible. A virus that started in China And to spread a lot in Europe and America, the species has changed over time
A new species that everyone is watching for British breed Also known as B.1.1.7, also known as VOC 202012/01, is the Variant of Concern officially announced on December 20 (12) 2020.
This strain has a major amino acid change in position 501, shifting from asparagine to tyrosine, known as N501Y, which is positioned to bind to ACE2 cell receptors, making the virus easier to bind to cells. As a cause for easy infection And spread easily But not about the severity of the disease and the immune system.
Later, there were more mutations than the British breed. Made in south africa The strains are similar to the British strains but with increased mutations in the amino acid location. On the 484 protein sprite with no glutamic conversion to lysine or E484K called B.1.351 or 501Y.V2 in position 484, it is involved in the immune system. That may affect the effectiveness of the vaccine. Therefore, special education and surveillance is needed for this breed.
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The Brazilian strains were found to have 19 mutations in the Amazon, Brazil, with additional mutations from the British and South African strains at additional 417 locations (K417N / E484K / N501Y), or simply P.1. Further studies are needed to determine how much the strain affects the immune system because there is one additional mutation associated with the immune system in position 417.
The need for genetic code studies to monitor surveillance. And compared with the epidemiology Including the immune system And the severity of the disease It is absolutely necessary and prevents the spread of new species from occurring. Especially the species that will avoid the immunity ofVaccine And will reduce the effectiveness of the vaccine
For in Thailand, there has been full surveillance. Especially those who come from abroad, whether from Europe orAmerica Currently at the center where I work Monitor mutations by detecting state quarantine species.EnglandAlready up to 7 cases
Of the seven, five are from England, one from the United States and one from France. Foreign species that arise Must be vigilant Not to cause an outbreak in our home Especially those who come from abroad And there must be a random inspection of the species that occur in our own home as well. That there are genetic changes So as not to spread rapidly Or vaccine-resistant strains originated in Thailand
The importance of studying science for students Therefore it is imperative to understand In this article
#Doctor Yong
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