Scientists have found that microbiome imbalances are linked to common allergies, eczema, asthma, and food allergies in children.
IS with reference to foreign media, it has been determined how all this can be related to the intestinal microbiome, the community of microorganisms such as bacteria, fungi and viruses living in the digestive system
The results of the study, published in the journal Nature Communications, may contribute to preventing the spread of allergies in children. Scientists at the University of British Columbia and Children’s Hospital in Canada have found that characteristics of the gut microbiome and early life exposures are linked to the development of common allergies. Although allergies have unique symptoms, the researchers wanted to find out if they share a common origin related to the gut microbiome of infants.
The study examined clinical assessments of 1,115 children whose data were followed from birth to five years of age. About half of these children had no evidence of allergies, but 592 were diagnosed with one or more allergic diseases by a doctor. Examining gut samples from three-month-old and then one-year-old children, researchers found traces of allergy-related bacteria in children up to five years of age. Bacterial footprint has been recognized as a sign of intestinal flora imbalance. This causes damage to the intestinal lining and an increased inflammatory response in the gut.
Courtney Hoskinson, lead author of the paper, noted that our bodies normally tolerate the millions of bacteria that live in our gut because it is so important to our health: “To tolerate this, the body must create a strong barrier between immune cells and limit inflammatory signals. This will activate those immune cells. A widespread disorder in these mechanisms has been detected before the development of allergies in babies.
Stuart Turvey, professor of pediatrics and lead author of the study, pointed out that the problem that causes the imbalance can be linked to how the baby is born, where it lives and exposure to drugs such as antibiotics, among other factors. Although antibiotics can destroy sensitive bacteria, breastfeeding is known to renew the bacteria in the baby’s gut and provide the necessary nutrients: “From these data, we can see that factors such as antibiotic use in the first year of life lead to allergic disorders later on.”
The scientists hope the results will be used to find treatments that correct the imbalance of gut flora.
