A study conducted in the US concluded that the risk of Parkinson’s disease is 76% higher among people with lesions of the gastrointestinal tract.
The authors of the study, scientists from Deaconita Beth Israel Medical Center, believe that more attention would be needed among those with a history of damage to the upper gastrointestinal tract – usually ulcers caused by the bacteria H. pylori, gastroesophageal reflux disease (GERD) or the use of non-steroidal anti-inflammatory drugs such as ibuprofen.
“A growing body of evidence suggests that, at least in a subset of people, Parkinson’s disease originates in the gut before affecting the central nervous system,” said e. in a statement Dr. Trisha S. Pasricha, neuro-gastroenterologist and director of clinical research at the Gut-Brain Axis Research Institute of the aforementioned center, but also a professor at Harvard Medical School.
“People often think of how the brain affects the gut, but the gut can have a profound effect on the brain in ways that we are just beginning to understand.
“Many people with Parkinson’s disease have gastrointestinal symptoms such as constipation and nausea for years – even decades – before developing motor symptoms such as difficulty walking or tremors,” the scientist said.
In the study, patients who had no history of Parkinson’s disease underwent an upper endoscopy – a procedure for imaging and detecting problems in the esophagus, stomach, and the first part of the small intestine, which together make up the gastrointestinal tract high
The patients were monitored for almost 20 years, with the scientists estimating that the risk of developing Parkinson’s disease was 76% higher among those with a history of damage to lining the upper gastrointestinal tract than among others, as shown in a report published by the journal JAMA Network Open.
On average, Parkinson’s disease was diagnosed 14.2 years after mucosal lesions were detected at upper endoscopy.
2024-09-25 21:03:00
#medical #examination #Parkinsons #disease #wounds #danger
