Crohn’s disease affects four million people around the world, and causes debilitating symptoms such as chronic fatigue, diarrhea, abdominal pain, weight loss and malnutrition, while a recent study revealed that it is linked to “bacteria in the mouth,” according to a report by the website “.Science Alert“.
What is Crohn’s disease?
Crohn’s disease is a type of inflammatory bowel disease that causes swelling and “inflammation” of the tissues in the digestive tract. This may lead to cramps, severe diarrhea, fatigue, weight loss and malnutrition.Mayo Clinic“.
The site of inflammation caused by Crohn’s disease in the digestive tract may differ from one person to another, and the most affected area is the small intestine, and this inflammation often spreads to the deep layers of the intestine.
Crohn’s disease can cause a lot of pain and fatigue, and can sometimes lead to life-threatening complications.
Once Crohn’s symptoms appear, the disease remains as a lifelong condition, and although there are ways to control those symptoms, there is currently no cure for it, according to Science Alert.
What are his reasons?
The exact causes of Crohn’s disease are not known and may be due to a number of complex and interrelated factors, including genetics and others linked to smoking and excessive activity in the gastrointestinal tract.
Research has shown that the “gut microbiome” plays an important role in the development of the disease.
The gut microbiome is made up of trillions of bacteria, viruses and fungi that have been present in the human body since birth.
This microbiome plays an important role in ensuring that our gut cells function properly, and the bacteria in our gut also help our immune cells function as they should, ultimately ensuring their effectiveness.
Several studies show that people with Crohn’s disease have a “less diverse” collection of gut bacteria and also have higher levels of certain types of bacteria that can lead to gut inflammation.
But it’s not just gut bacteria that show signs of dysfunction in people with Crohn’s disease. Research shows that bacteria in the mouth may also be important in this inflammatory condition.
The “human mouth” contains the second largest number of bacteria after the intestine, and humans swallow millions of bacteria in saliva every day.
Studies show that people with Crohn’s disease have different bacteria in their mouths compared to those without the condition.
According to “Science Alert”, there are certain types of bacteria present in the mouth that may play a role in infection with “Crohn”.
There are also fewer types of bacteria that are more commonly found in the intestines of people with Crohn’s disease than in people with a “healthy mouth”.
Research in humans indicates that one oral bacteria in particular, called Veillonella parvula, is abundant in the guts of people with Crohn’s disease.
Research in mice reveals that inflammation “makes it easier for certain types of bacteria to grow, leading to an overactivation of immune cells and thus a widening of inflammation.”
If the same is true of the oral bacteria associated with the disease, this could indicate that bacterial overgrowth and inflammation in the mouth is a possible root cause of Crohn’s.
2023-07-27 06:19:50
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