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The Lancet Publishes Prof. Su Lim’s Groundbreaking Thesis on Type 2 Diabetes Treatment

Prof. Su Lim’s research team published a thesis on diabetes treatment for the past 20 years in ‘Lancet’
Elucidation of epidemiology, pathophysiology, screening, diagnosis, prevention method, development pattern and direction of type 2 diabetes
Presented as a patient-centered multidisciplinary care solution in which doctors and patients share treatment guidelines

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Professor Lim Soo (Department of Endocrinology and Metabolism, Seoul National University Bundang Hospital)

Seoul National University Bundang Hospital, Department of Endocrinology and Metabolism, Professor Su Lim’s research team (corresponding author: Professor Melanie Davies, University of Leicester Diabetes Research Center, UK) published a prestigious medical journal. He published a comprehensive thesis on the epidemiology and pathophysiology of type 2 diabetes, screening and diagnosis, complications, prevention and management methods, as well as the development of diabetes treatment over the past 20 years and future directions.

Type 2 diabetes is a chronic disease that is so common that it accounts for 90% of the 537 million people with diabetes worldwide.

According to this study, it is important to detect the disease early and prevent it in order to prevent complications of diabetes and death from it. In particular, in the case of the high-risk group, it is helpful to prevent or delay diabetes if managed by weight loss through diet and exercise before the disease occurs.

With the recent development of precision medicine, understanding of diabetes has increased, as well as new treatments being developed, and the possibility of targeting treatment toward a complete cure has increased. The paradigm of treatment is also changing from simple blood sugar control to a holistic treatment centered on the individual patient.
That is, it is recommended to actively use SGLT-2 inhibitors and GLP-1 analogs, which are new drugs for diabetes treatment.

However, ‘clinical inertia’ remains a stumbling block in diabetes treatment, which means that medical staff are reluctant to implement new treatments and want to stick to existing methods.

For example, in a global survey of 1677 medical staff, 67% of respondents were aware of published data on new hypoglycemic therapies, and 81.6% agreed that there would be clinical benefit from early initiation of such therapies. However, it was reported that 46.1% did not actively use these therapies and applied them only at a very late stage.

In addition, it is worrisome that many countries are still using products that increase the risk of hypoglycemia or weight gain among older drugs that have been on the market.

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‘Clinical inertia’ is a complex problem in which reduced treatment time, limited available drugs, and high medical costs are intertwined like a thread, so to overcome this, the research team proposes to utilize a patient-centered, multidisciplinary treatment method.

It is believed that clinical inertia can be most effectively alleviated when doctors and patients share appropriate treatment guidelines, and not only doctors but also nurses, pharmacists, and nutritionists work together as a multidisciplinary team to treat patients.

In recent years, new technologies for diabetes management have been widely used, such as continuous blood glucose monitors and automatic insulin injectors. , meal calorie counting, and body composition analysis devices are widely used in the management of diabetic patients.

Professor Lim Soo said, “This thesis is a compilation of studies related to type 2 diabetes published over the past 20 years, and it is very meaningful as it describes the direction that diabetes treatment should go in the future.” We look forward to a change in the treatment paradigm, and we will continue our research to prevent complications and improve the quality of life of diabetic patients.”

Meanwhile, this study was published in the world-renowned SCI journal, The Lancet.

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2023-04-26 02:31:58

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