Delivery time2023-09-05 13:44
brain hemorrhage
[제작 박이란 일러스트]
(Seoul = Yonhap News) Hanseonggan = There are not a few studies showing that statin-type hyperlipidemia drugs can increase the risk of recurrence of internal bleeding in patients who have suffered intracerebral hemorrhage. According to this, the risk of recurrence increases, especially when the blood cholesterol level drops significantly. Taking statins lowers cholesterol levels.
Intracerebral hemorrhage occurs when a thin blood vessel inside the brain ruptures and bleeds. It can be caused by high blood pressure, trauma, or increased abdominal pressure. The hemorrhage itself and the increase in intracranial pressure caused by the hemorrhage cause severe damage to the brain.
However, studies have shown that statins are not associated with the risk of recurrence of cerebral hemorrhage and rather have the effect of reducing the risk of cerebral infarction.
A research team led by Professor David Kaist, a neurologist at Odense University Hospital in Denmark, studied 15,151 people who suffered their first intracerebral hemorrhage, and the average duration from 30 days after the intracerebral hemorrhage to another stroke or death was 3.3 years. A follow-up study revealed this, Science Daily reported 4 .
The research team included (1) a group (1,959 patients) with recurrence of stroke, whether ischemic or hemorrhagic, during the follow-up period and a control group (7,400 patients) who did not have recurrence of stroke who were matched by age, sex, etc. (2) A group with ischemic stroke (cerebral infarction) (1,073 patients) and a control group without cerebral infarction (4,35 patients) (3) A group with recurrent intracerebral hemorrhage (984 patients) and a control group without recurrence (3,755 patients) ) was divided by
The research team then compared the ratio of statin users and non-users in the experimental and control groups in each group.
As a result, in the group with ischemic or hemorrhagic stroke, 39% of the experimental group and 41% of the control group were statin users.
When other variables such as high blood pressure, diabetes and alcohol consumption were taken into account, statin users had a 12% lower risk of stroke.
In the ischemic stroke group, statin users were 40% in the experimental group and 42% in the control group.
After accounting for other variables, statin users had a 21% lower risk of ischemic stroke.
In the group with recurrent intracerebral hemorrhage, statin users were 39% in the experimental group and 41% in the control group.
When other variables were considered, it was analyzed that there was no association between statin intake and intracerebral hemorrhage.
These results show that statin administration does not increase the risk of recurrence of intracerebral hemorrhage, but rather lowers the risk of cerebral infarction, the research team explained.
This would be welcome news for those taking statins with a history of hemorrhagic brain hemorrhage, the researchers added.
Hemorrhagic stroke accounts for about 13% of all stroke patients. These include intracerebral hemorrhage and subarachnoid hemorrhage.
The arachnoid is a thin membrane that covers the brain and spinal cord in the lower layer of the skull, resulting from damage to the brain’s superficial arteries underneath. It is mainly caused by the rupture of an aneurysm, which is formed like a hole in an artery.
The 30-day survival rate for intracerebral hemorrhage has hardly improved over the past 30 years.
The findings were published in the latest issue of Neurology, the journal of the American Academy of Neurology.
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