Research results that reveal the risk of cardiovascular disease caused by differences in activity in cancer survivors before and after cancer diagnosis are attracting attention in Korea.
The research team of Professors Kim Hyeon-chang, Professor Lee Ho-gyu, and Lecturer Hyeok-hee Lee of the Department of Preventive Medicine at Yonsei University College of Medicine announced on the 9th that if you engage in physical activity before cancer diagnosis but stop physical activity after diagnosis, the risk of developing cardiovascular disease increases by up to 43%.
Professor Kim Hyeon-chang said, “This study is significant in that it is the first study in Korea to investigate the risk of cardiovascular disease according to changes in physical activity in cancer survivors, which was previously unknown,” and added, “It is best for cancer survivors to make continuous efforts to increase their activity level if possible, rather than reducing it. “He said.
The results of this study were published in the international academic journal European Heart Journal (IF 39.3).
According to the 2020 national cancer registration statistics, the 5-year relative survival rate of domestic cancer patients is 71.5%. Relative survival rate is a comparison of the survival rate of cancer patients and the expected survival rate of the general public. It is the probability of cancer patients surviving for 5 years compared to the general population. This means that 7 out of 10 cancer patients survive for more than 5 years.
As the number of cancer survivors increases, strategies to prevent cardiovascular disease, the main cause of death among cancer survivors, are becoming important. As a result of approximately 13.6 years of follow-up of 11,093 people participating in the Atherosclerosis Risk in Communities Study (ARIC), cancer survivors had a 37% higher risk of cardiovascular disease, heart failure, and stroke compared to the control group. %, 52%, 22% higher.
The American Cancer Society’s 2022 guidelines recommend that cancer survivors engage in at least 150 minutes of moderate-intensity physical activity or at least 75 minutes of vigorous-intensity physical activity per week. Converted to MET (Metabolic Equivalent of Task), it is about 600. MET is the amount of oxygen consumed per minute per kilogram divided by 3.5, and is an indicator of the amount of energy consumed during physical activity.
The research team investigated the risk of cardiovascular disease in cancer survivors according to changes in physical activity before and after cancer diagnosis. The subjects of the study were 150,433 adults aged 20 or older who were diagnosed with cancer between 2011 and 2013 and were 3-year cancer survivors who underwent national health examinations within 2 years before and 3 years after diagnosis.
Subjects were divided into an inactive group (0), an activity group below recommendations (1~599), and an activity group meeting recommendations (above 600) according to MET, and the risk of cardiovascular disease was examined.
Regardless of the amount of physical activity before cancer diagnosis, the greater the amount of physical activity after diagnosis, the lower the cardiovascular risk. Even if one did not engage in physical activity before diagnosis, the risk decreased by 19% and 20%, respectively, if activity was below or at a level recommended after diagnosis.
↑Cardiovascular disease risk ratio according to changes in physical activity
Conversely, if you maintained physical activity before diagnosis but stopped doing so after diagnosis, your risk of cardiovascular disease increased. If the patient was active at a level that fell below or met the recommendations before diagnosis and then became inactive after diagnosis, the risk increased by 24% and 43%, respectively.
Even when the cardiovascular risk according to the change in physical activity was continuously examined, the greater the increase in physical activity after the cancer diagnosis compared to before the cancer diagnosis, the greater the decrease in risk, and the further it decreased, the more the risk increased.
2023-11-09 12:44:00
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