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The Impact of COVID-19 on the Brain: Long-Term Neurological Complications and Potential Implications

On August 13, 2023 Assoc.Prof.Dr.Theera Worathanarat or “Doctor Theera” Faculty of Medicine Chulalongkorn University Facebook post updates the issue. COVID-19 stating that

The COVID-19 virus and the brain

It is well known today that the infectionCOVID-19 virus or SARS-CoV-2 is not only infectious in the respiratory system but can spread to almost every system in the body It has been proven by research from around the world.

Not many patients after recovering from the initial infection back with persistent abnormalities or reappear after recovering from illness and is continuing in the long run known as Long COVID or Post-COVID conditions

Symptoms that occur in the long run occur in every system in the body by resulting in illness impair performance in daily life worsen the quality of life Both in school, work and personal life. Including various expenses It is a burden on patients, families and society.

common symptoms There are both tired and exhausted things. muscle and joint pain including problems in the vital systems of the body both heart and blood vessels respiratory system digestive system urinary system And very important is the brain and nervous system. Which usually comes with problems with concentration, emotions, thoughts, memory, etc.

Mechanisms that cause abnormalities in Long COVID occur from many mechanisms, such as the presence of the virus or its fragments remaining in the body’s organs, the tissues or cells in that system. Destroyed by viruses, autoimmunity, infections provoke chronic inflammatory processes, including infection with COVID-19. Encourage infectious viruses that are hidden in the body to become active, etc.

One of the studies definitively proved that viral fragments remain in the brain after infection.COVID-19 It comes from a German research team. The study was published in bioRxiv last April. by detecting the cortical fragments of the virus both in the brain bone marrow of the skull and the cortex from the bodies of patients who died from COVID-19 About half of the total which led to the medical hypothesis that

The remains of the virus especially in the marrow part of the skull It is likely to lead to inflammation. interfere with brain function and/or destroy nerve cells in the brain This will cause problems with brain and nervous system abnormalities in Long COVID patients.

The German team conducted further studies and proposed that the above mechanisms could be used to explain brain and nervous system problems from other diseases. that are similar as well It was published in the medical science journal Cell on August 9th.

protection against infection or not repeating is the best

Live a conscious life, don’t be careless, always protect yourself.

wearing a mask correctly It will greatly reduce the risk.

refer

1. SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19. bioRxiv. 5 April 2023.

2. Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell. 9 August 2023.

2023-08-12 23:47:00

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