PubMed Abstract

Acute COVID-19 severity markers predict post-COVID new-onset psychiatric disorders: A 2-year cohort study of 34,489 patients

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Acute COVID-19 severity markers predict post-COVID new-onset psychiatric disorders: A 2-year cohort study of 34,489 patients

New-onset psychiatric disorders are frequent after COVID-19. We aim to determine whether acute COVID-19 severity markers can predict post-COVID new-onset psychiatric disorders. We conducted an electronic health records (EHR) cohort study of patients hospitalized for COVID-19 and without any known history of psychiatric disorders. Patients were included between January 2020 and September 2022 in one … Read more

PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Background: Anti-COVID-19 hyperimmune immunoglobulin (hIG) can provide standardized and controlled antibody content. Data from controlled clinical trials using hIG for the prevention or treatment of COVID-19 outpatients have not been reported. We assessed the safety and efficacy of subcutaneous anti-COVID-19 hyperimmune immunoglobulin 20% (C19-IG20%) compared to placebo in preventing development of symptomatic COVID-19 in asymptomatic … Read more

Cryo-EM captures early ribosome assembly in action

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Ribosome biogenesis is a fundamental multi-step cellular process in all domains of life that involves the production, processing, folding, and modification of ribosomal RNAs (rRNAs) and ribosomal proteins. To obtain insights into the still unexplored early assembly phase of the bacterial 50S subunit, we exploited a minimal in vitro reconstitution system using purified ribosomal components … Read more

Effect of Altitude on Respiratory Functional Status in COVID-19 Survivors: Results from a Latin American Cohort-FIRCOV

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Laura Gochicoa-Rangel, Santiago C. Maple, Carlos Aguirre-Franco, Wilmer Madrid-Mejia, Monica Gutierrez-Claveria, Lorraine Noriega-Aguirre, Patricia Schonffeldt-Guerrero, Agustin Acuna-Izcaray, Arturo Cortes-Telles, Luisa Martinez-Valdeavellano, Federico Isaac Hernandez-Rocha, Omar Ceballos-Zuñiga, Rodrigo Del Rio Hidalgo, Sonia Sanchez, Erika Meneses-Tamayo, and Ivan Cherrez-Ojeda; and on Behalf of the Respiratory Physiology Project in COVID-19 (FIRCOV). Effect of altitude on respiratory functional status … Read more

Severe SARS-Cov2 pneumonia in vaccinated patients: a multicenter cohort study

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Vaccination reduces risk of infection, hospitalization, and death due to SARS-Cov2. Vaccinated patients may however experience severe SARS-Cov2 disease. The objective was to describe clinical features of vaccinated patients requiring intensive care unit (ICU) admission due to SARS-Cov2 infection and compare them to a published cohort of unvaccinated patients. We performed a multicenter cohort study … Read more

Undergraduate Surgery Student Limits During the COVID-19 Pandemic

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Objective: Know the limitations students have encountered in their undergraduate surgery course during the COVID-19 pandemic. Method: Through an online questionnaire, students were asked to evaluate the surgery degree course, the limits encountered during the course, both those perceived by themselves and the limits they perceived in the teachers. Questions were asked about the overall … Read more

Resistance training and clinical status in patients with postdischarge symptoms after COVID-19: protocol for a randomized controlled crossover trial “The EXER-COVID Crossover Study”

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Background: Physical exercise induces a coordinated response of multiple organ systems, including the immune system. In fact, it has been proposed that physical exercise may modulate the immune system. However, the potential effect of an exercise program on COVID-19 survivors has not been investigated. Thus, the aim of this study is to evaluate the modifications … Read more

[Prise en charge médicale du Covid-19, hors réanimation]

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

. 2022 May;72(5):505-510. – – [Article in French] Affiliations Expand Affiliations 1 Department of Infectious and Tropical Diseases, Hospices Civils de Lyon, France. 2 Department of Infectious and Tropical Diseases, Hospices Civils de Lyon, France – International Center for Infectious Disease Research (CIRI), Inserm 1111, Claude-Bernard Lyon-1 University, National Center for Scientific Research, Joint Research … Read more

Myocardial Infarction in a 29-Year-Old Woman Leads to Diagnosis and Treatment of a Rare Disease

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

Case Reports . 2022 Jul; 162 (1): e49-e52. – doi: 10.1016/j.chest.2022.01.066. – Affiliations Expand Affiliations 1 Cardiology Department, Ambroise Paré Hospital, Assistance Publique des Hôpitaux de Paris, Boulogne, University of Versailles-Saint Quentin en Yvelines, Paris, France; Competence Center for Hereditary Hemorrhagic Telangiectasia Disease, Ambroise Paré Hospital, Assistance Publique des Hôpitaux de Paris, Boulogne, University of … Read more

[What have we missed because of COVID-19? Missed diagnoses and delayed follow-ups. SESPAS Report 2022]

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PubMed: A Randomized Double-Blind Placebo-Controlled Clinical Trial Evaluating the Efficacy of Subcutaneous Hyperimmune Immunoglobulin Against COVID-19 in Asymptomatic Individuals with SARS-CoV-2 Infection for Disease Prevention.

The COVID-19 pandemic and the associated public health emergency have affected patients and health services in non-COVID-19 pathologies. Several studies have shown its dissociation from health services, with a decrease in emergency department visits, in hospital admissions for non-COVID-19 pathologies, as well as in the reported weekly incidence of acute illnesses and new diagnoses in … Read more