Ribosome biogenesis is a fundamental multi-step cellular process in all domains of life that involves the production, processing, folding, and modification of ribosomal RNAs (rRNAs) and ribosomal proteins. To obtain insights into the still unexplored early assembly phase of the bacterial 50S subunit, we exploited a minimal in vitro reconstitution system using purified ribosomal components … Read more
Laura Gochicoa-Rangel, Santiago C. Maple, Carlos Aguirre-Franco, Wilmer Madrid-Mejia, Monica Gutierrez-Claveria, Lorraine Noriega-Aguirre, Patricia Schonffeldt-Guerrero, Agustin Acuna-Izcaray, Arturo Cortes-Telles, Luisa Martinez-Valdeavellano, Federico Isaac Hernandez-Rocha, Omar Ceballos-Zuñiga, Rodrigo Del Rio Hidalgo, Sonia Sanchez, Erika Meneses-Tamayo, and Ivan Cherrez-Ojeda; and on Behalf of the Respiratory Physiology Project in COVID-19 (FIRCOV). Effect of altitude on respiratory functional status … Read more
Vaccination reduces risk of infection, hospitalization, and death due to SARS-Cov2. Vaccinated patients may however experience severe SARS-Cov2 disease. The objective was to describe clinical features of vaccinated patients requiring intensive care unit (ICU) admission due to SARS-Cov2 infection and compare them to a published cohort of unvaccinated patients. We performed a multicenter cohort study … Read more