Researchers at Weill Cornell Medicine have found that protein built-up in astrocytes could trigger abnormal antiviral activity and memory loss in those with dementia. The study could lead to treatments that reduce immune activity in astrocytes to improve cognition. Drugs that target the immune pathways already exist and may be repurposed for dementia treatments. Previous research shows links between viral infections and cognitive dysfunction, which could be exacerbated by astrocyte immune activity. The team is now studying how TDP-43 changes the antiviral activities in astrocytes and whether it increases brain susceptibility to viral pathogens.

Researchers at Weill Cornell Medicine have found that protein built-up in astrocytes could trigger abnormal antiviral activity and memory loss in those with dementia. The study could lead to treatments that reduce immune activity in astrocytes to improve cognition. Drugs that target the immune pathways already exist and may be repurposed for dementia treatments. Previous research shows links between viral infections and cognitive dysfunction, which could be exacerbated by astrocyte immune activity. The team is now studying how TDP-43 changes the antiviral activities in astrocytes and whether it increases brain susceptibility to viral pathogens.

As we age, our cognitive abilities undergo slow but significant changes. It is not uncommon for some individuals to experience memory loss, difficulty concentrating, and other cognitive impairments. While some of these changes are considered a normal part of aging, researchers have discovered a link between cognitive decline and problems with astrocytes – a type … Read more

Advanced brain aging may predict dementia risk in patients with ischemic heart disease, particularly those with diabetes and obesity, according to a UK Biobank study. The research suggests “central adiposity as an indicator of visceral fat” accelerates brain aging in the presence of IHD, said lead author Elisa Rauseo, of Queen Mary University and St Bartholomew’s Hospital, London. Visceral fat promotes systemic inflammation, which could partly underlie IHD-associated brain aging and dementia, the study said. Brain scans indicating age beyond patients’ actual years could encourage anti-dementia measures among younger people, the researchers said.

Advanced brain aging may predict dementia risk in patients with ischemic heart disease, particularly those with diabetes and obesity, according to a UK Biobank study. The research suggests “central adiposity as an indicator of visceral fat” accelerates brain aging in the presence of IHD, said lead author Elisa Rauseo, of Queen Mary University and St Bartholomew’s Hospital, London. Visceral fat promotes systemic inflammation, which could partly underlie IHD-associated brain aging and dementia, the study said. Brain scans indicating age beyond patients’ actual years could encourage anti-dementia measures among younger people, the researchers said.

As we age, our brains undergo a natural process of aging that can lead to cognitive decline and an increased risk of developing conditions like dementia. But recent research has suggested that this process may be linked to heart health, with some experts suggesting that the cardiovascular systems in our bodies may play a critical … Read more

Rephrased: Using Eye Health to Detect Alzheimer’s Disease – A Video Presentation

Rephrased: Using Eye Health to Detect Alzheimer’s Disease – A Video Presentation

CNN | CNN Indonesia Saturday, 25 Mar 2023 16:26 WIB Jakarta, CNNIndonesia — A study says that eye health can help diagnose Alzheimer’s disease. The study appears in the February issue of the journal Acta Neuropathologica. Scientists looked at retinal and brain samples from 86 people aged 14 and over. The samples show that there … Read more

4 Benefits of Consuming Beef Liver, Reducing the Risk of Anemia, How come? – Tempo.co style

TEMPO.CO, Jakarta – Beef liver Also known as organ meat or offal. It is often processed into a variety of dishes. Besides being delicious to eat, beef liver also provides various types of nutrients and minerals. These include calories, vitamin B12, vitamin B6, vitamin A, zinc and phosphorus. Also selenium, copper and iron, as cites … Read more

Even though it’s cheap, this diabetes drug is believed to reduce the risk of Alzheimer’s by up to 54 percent

Even though it’s cheap, this diabetes drug is believed to reduce the risk of Alzheimer’s by up to 54 percent

REPUBLIKA.CO.ID, JAKARTA — a diabetes medication which can be purchased at a low price turned out to have great potential in the prevention of Alzheimer’s disease. According to studies, a drug called Actos or pioglitazone This can reduce the risk of disease Alzheimer up to 54 percent. “Remember dementia often occurs for several years before … Read more

Want to protect the brain from Alzheimer’s? Try High Intensity Exercise, Just Six Minutes!

Want to protect the brain from Alzheimer’s?  Try High Intensity Exercise, Just Six Minutes!

High-intensity exercise can be a non-pharmacological approach to Alzheimer’s. REPUBLIKA.CO.ID, JAKARTA — A new study reveals that exercising at high intensity for six minutes can lengthen brain health and delay illness Alzheimer and Parkinsons. Studies published in Journal of Physiology on Jan. 11 it found short, high-intensity cycling can increase the production of a protein … Read more

Division about ‘breakthrough’ in the fight against Alzheimer’s: ‘It’s spectacular’ | Health

Division about ‘breakthrough’ in the fight against Alzheimer’s: ‘It’s spectacular’ |  Health

17 jan 2023 om 05:06 Six minutes of vigorous exercise a day may delay Alzheimer’s by ten years. New blood tests may enable us to detect the disease much more quickly. And a promising Alzheimer’s drug has even been approved in the United States. The hopeful messages about the fight against Alzheimer’s follow each other … Read more

Alzheimer’s: These are the 7 worst foods that increase risk according to a study

Alzheimer’s: These are the 7 worst foods that increase risk according to a study

Today the causes of the degenerative Alzheimer’s disease are still unknown. However, some scholars link the excessive consumption of certain foods to the onset of the disease. Let’s see what they are and if you are a regular consumer. ©liudmilachernetska/123rf Alzheimer’s is a progressive degenerative disease that damages some brain cells, leading to an irreversible … Read more

An American team focuses its efforts on a new experimental Alzheimer’s vaccine

An American team focuses its efforts on a new experimental Alzheimer’s vaccine

The Gates Biomanufacturing Facility at the Anschutz Medical Campus of the University of Colorado (United States) has announced the completion of the production process of an experimental recombinant protein against Alzheimer’s disease that will be tested as a vaccine in clinical trials. This vaccine, known as AV-1980R, can be used to … The Gates Biomanufacturing … Read more

Seriously, nose picking potentially causes Alzheimer’s

Seriously, nose picking potentially causes Alzheimer’s

Jakarta, CNN Indonesia – The habit of pinching the nose can actually end Alzheimer’s. How could it be? A group of scientists from Griffith University in Australia has tested a bacterium called Chlamydia pneumoniae, which can infect humans and cause pneumonia. The bacteria are also found in many human brains, which are affected by dementia. … Read more