/Seoul Asan Medical Center
A new study has shown that even women who have had breast cancer in the past as carriers of a breast cancer risk gene do not have a high risk of breast cancer recurrence due to pregnancy.
A research team at the University of Genoa in Italy recently published the results of this study in the Journal of the American Medical Association (JAMA). This is the result of an 8-year follow-up study conducted by researchers on 4,732 women under the age of 40 who had early-stage breast cancer and had BRCA1 or BRCA2 gene mutations that make them at high risk for breast cancer.
According to the study, the average age of the study subjects at the time of breast cancer diagnosis was 35 years old, and during the 8-year follow-up period, 659 women, or 22% of these women, became pregnant. When the researchers compared the breast cancer recurrence rates between these women and 4,073 women who did not, they found that the risks of breast cancer recurrence were almost equal. Matteo Lambertini, professor of oncology at the University of Genoa in Italy and lead author of the paper, said, “This is the first large-scale study to show whether pregnancy is stable in women who have BRCA1 or BRCA2 genes and have breast cancer.” He explained that “many medical staff advise women with these genetic risk factors not to become pregnant due to concerns that the risk of recurrence may increase,” adding, “The main message of this study is that the risk of recurrence does not increase if these women become pregnant.” .
According to the U.S. National Cancer Institute (NCI), about 13% of all women develop breast cancer at some point in their lives. In particular, if you have a BRCA gene mutation, the risk of developing breast cancer in both breasts is much higher. The risk of breast cancer for women with BRCA1 and BRCA2 is over 50% and over 45%, respectively. They are at high risk of developing cancer at a young age, such as ovarian cancer.
2024-01-21 03:15:00
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