Tokyo Medical and Dental University recently published a study indicating that a type of bacteria that often causes periodontal disease is highly related to the regeneration and reorganization of heart tissue.
This study published in the International Journal of Oral Science points out that Porphyromonas Gingivalis, a common bacterium in the mouths of patients with periodontal disease, in addition to causing gum disease In addition to dental disease, it can also have an impact on the heart.
Professor Yuka Shiheido Watanabe, one of the leaders of the study, pointed out that in previous studies of myocardial infarction, Porphyromonas gingivalis has been found in patients with cardiovascular embolism, but how exactly does this bacterium affect the cardiovascular system? Cardiovascular effects are unknown.
The team’s research found that Porphyromonas gingivalis can affect the normal production of autophagosomes and lysosomes, and affect the renewal of cardiomyocytes, causing cardiovascular problems.
In order to further understand the detailed impact of P. gingivalis, the research team removed “Gingipain”, a protease mainly secreted by this bacterium, and transplanted the original P. gingivalis together into experimental mice. Observe on your body.
Experimental results found that the survival rate of experimental mice infected with P. gingivalis that lost curcumin was much higher than that of mice with original infection source. Therefore, curcumin is the key.
The team stated that curcumin affects the accumulation of excessive autophagosomes in myocardial tissue, causing abnormalities in cardiovascular cells, slowing down the renewal of vascular cells, increasing the chance of thrombosis, and thus increasing the incidence of myocardial infarction.
Porphyromonas gingivalis is most likely to breed when you suffer from periodontal disease. Therefore, if you can effectively clean your mouth every day and reduce the occurrence of periodontal disease, you can reduce the chance of the body being infected with Porphyromonas gingivalis and also reduce the risk of periodontal disease in disguise. The probability of myocardial infarction.
(Source of first picture:Pixabay）
2023-12-11 17:53:48
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