A study has found that taking aspirin to prevent stroke is not effective. (Photo = DB)
[메디컬투데이=한지혁 기자] Studies have shown that taking aspirin to prevent stroke is not effective.
The results of a study investigating the stroke prevention effect of low-dose aspirin were published in the journal ‘JAMA Geriatrics’.
Stroke is a fatal disease that can occur when a sufficient amount of blood is not supplied to the brain or when blood vessels in the brain bleed. According to statistics, more than 795,000 people in the United States suffer from a stroke each year. In addition, more than 1 in 6 deaths due to cardiovascular disease are related to stroke.
Stroke prevention is essential for reducing overall mortality. Currently, aspirin, a drug that is also used as an analgesic, is widely used to prevent stroke.
A meta-analysis study showed that taking low-dose aspirin may help reduce the risk of stroke. However, other studies have concluded that aspirin may actually increase the risk of intracranial bleeding.
Elderly people are at increased risk of brain hemorrhage due to fragility of small blood vessels and increased risk of falls. These factors may reverse the balance between the risks and beneficial effects of taking aspirin.
Recently, a study investigated the effect of low-dose aspirin on the risk of stroke and bleeding in older adults. 19,114 elderly participants, with an average age of 74 years, were recruited and randomly assigned to one of two groups, each taking either 100 mg of aspirin daily or the same dose of a placebo.
The average follow-up for the participants was 4.7 years. As a result of the analysis, the researchers confirmed that the effect of low-dose aspirin on the incidence of stroke was clinically insignificant.
The incidence of ischemic stroke in the aspirin group and control group was 1.5% and 1.7%, respectively, and hemorrhagic stroke was 0.5% and 0.4%, respectively. In addition, in the case of participants who took aspirin, the probability of experiencing intracranial hemorrhage was 1.1%, which was rather high compared to 0.8% of the control group.
The experts said, “This study supports the findings of previous studies that routine use of aspirin in the general adult population has limited benefit, and may cause bleeding side effects, especially in the elderly.”
According to recently published guidelines in the United States, adults over the age of 60 are advised to refrain from daily intake of aspirin for the prevention of cardiovascular disease.
Experts say that it is helpful to prevent stroke in more conservative ways than aspirin, such as regular exercise and a healthy diet, and that stroke symptoms, such as paralysis on one side of the body or slurred speech, must be sought as soon as possible. Emphasized.
Medical Today Reporter Han Ji-hyeok (hanjh3438@mdtoday.co.kr)
[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]
2023-08-07 22:44:26
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