The reaction of immune cells inside the protective covering that surrounds the brain could contribute to the cognitive decline that occurs in people with chronic high blood pressure, according to a study supported by the National Institutes of Health in the United States of America (NIH), reported Xinhua Agency, taken from by Agerpres.
This study, published in the journal Nature Neuroscience, could shed light on new ways to counteract the effects of high blood pressure on cognition, the NIH announced in a press release.
Using a mouse model of high blood pressure, researchers in the United States found in the cerebrospinal fluid and in the brain abnormally high levels of interleukin-17 (IL-17), a chemical normally released in the body to activates the immune system.
A previous study showed that a high-salt diet increased IL-17 in the gut, which was followed by cognitive impairment.
“The role of immune signaling in cognitive decline is critically important to understand,” said Roderick Corriveau, program director at the US National Institute of Neurological Disorders and Stroke. “These findings provide new insight into how signaling from the immune system might contribute to the symptoms of cognitive decline that ultimately lead to the diagnosis of dementia,” he added.
2024-01-09 22:08:55
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