Home » Health » Stem cell transplantation cures leukemia in AIDS patients, the third case in the world is published in the journal “Nature Medicine”- The News Lens Key Comment Network

Stem cell transplantation cures leukemia in AIDS patients, the third case in the world is published in the journal “Nature Medicine”- The News Lens Key Comment Network

what we want you to know is

In 2013, the medical team performed a bone marrow transplant on the man using stem cells from a female donor with a rare CCR5 mutation. This mutated gene has been found in the past to prevent HIV from entering cells. The “Düsseldorf patient” then stopped using anti-HIV treatment in 2018. The medical team continued to test for four consecutive years, but no signs of HIV relapse were found in his body.

(Central News Agency) The male patient known as the “Düsseldorf patient” not only cured leukemia after receiving stem cell transplantation, but also became the third AIDS cure in the world to be published in a scientific journal.

Agence France-Presse reported that the study was published in a well-known international journalNature Medicine, the case is a 53-year-old male whose name has not been released, nicknamed “Düsseldorf Patient”. He was diagnosed with HIV in 2008, and three years later suffered from the life-threatening blood cancer “Acute Myeloid Leukemia”.

In 2013, the medical team performed a bone marrow transplant on the man using stem cells from a female donor with a rare CCR5 mutation. This mutated gene has been found in the past to prevent HIV from entering cells.

The “Düsseldorf patient” then stopped using anti-HIV treatment in 2018. The medical team continued to test for four consecutive years, but no signs of HIV relapse were found in his body.

Photo Credit: Nature Medicine (2023)
The research team followed up after the operation, using in situ hybridization to track the presence of HIV virus genes in the lymph nodes, duodenum and rectal sections of the cases.

The study, published in the journal Nature Medicine, states that “this third case of HIV-1 cure provides valuable insights into future treatment strategies.”

Two other cases of successful cure of AIDS by stem cell transplantation were published in scientific journals before. The two patients were from Berlin, Germany and London, England, and both also suffered from AIDS and cancer.

In addition, during several different scientific seminars in the past (2022), it was announced that two patients with cancer and AIDS were cured by similar treatments, namely the “New York patient” and the “City of Hope patient”. Scientific journals are officially published. However, ABC News included unpublished cases in its calculations, causing some media to identify the “Dusseldorf patient” as the fifth cured case in the world.

news source

further reading

[Join key comment network members]wonderful and good articles are sent directly to your mailbox every day, and special e-newspapers such as editor’s selection, current affairs selection, art and literature weekly are exclusively available every week. You can also leave a message to discuss the content of the article with the author, reporter, and editor. Click to become a member for free now!

Responsible editor: Zhu Jiayi
Draft Editor: Weng Shihang

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.