Home » Health » Scientists have discovered that melanocyte stem cells become stuck inside hair follicles, leading to hair greying, according to a study in the journal Nature. Researchers used scans and lab techniques to study how hair turns grey in mice, finding that the stem cells would get stuck in the hair follicle bulge as they aged, thus failing to produce pigment. The study suggests that the findings could lead to a potential way to reverse grey hair by helping jammed stem cells to move between developing hair follicle compartments.

Scientists have discovered that melanocyte stem cells become stuck inside hair follicles, leading to hair greying, according to a study in the journal Nature. Researchers used scans and lab techniques to study how hair turns grey in mice, finding that the stem cells would get stuck in the hair follicle bulge as they aged, thus failing to produce pigment. The study suggests that the findings could lead to a potential way to reverse grey hair by helping jammed stem cells to move between developing hair follicle compartments.

For most of us, the sight of our first grey hair can be quite alarming. It’s a hallmark of aging – a reminder that time is passing and, whether we like it or not, our bodies are changing. But have you ever wondered why hair turns grey as we get older? Is it just a necessary part of the aging process, or is there something deeper at play? Scientists have been studying this phenomenon for years, and have finally discovered what exactly causes our hair to go grey. In this article, we’ll take a closer look at their findings and explore the science behind why our hair loses its color.


According to a recent study published in the scientific journal Nature, scientists have discovered the reason why human hair turns gray as we age. The study reveals that melanocyte stem cells become stuck inside the hair follicle, preventing them from producing pigment.

For the study, scientists spent two years examining individual cells in the fur of mice to determine the aging process of hair. They used special scans and lab techniques to closely examine the melanocyte stem cells responsible for controlling hair color. They discovered that the pigment-producing part of a stem cell changes as mice mature. As hair ages and grows back, melanocyte stem cells become fixed in a part of the hair follicle called the hair follicle bulge, disrupting their ability to mature fully as melanocytes. This ultimately results in hair turning gray, white or silver, as no pigment is being produced.

Mayumi Ito, the author of the study and a dermatology professor at New York University’s Grossman School of Medicine, believes that the study is a significant step forward in understanding the phenomenon of graying. He explained that the loss of chameleon-like function in melanocyte stem cells is responsible for greying and loss of hair color.

The findings also suggest the potential to reverse or prevent gray hair in humans by helping jammed cells move again between developing hair follicle compartments. However, further research is needed to investigate if the same mechanism applies to humans.

Overall, the study offers valuable insight into the biological process of aging and how it affects our appearance. While hair turning gray is a natural part of aging, this research raises the possibility of preventing or reversing the process in the future.


So now we know the science behind why our hair turns grey as we age. It turns out that the depletion of melanocytes, the cells that produce pigment, can be attributed to a complex interplay of genetics, hormonal changes, and stress. While there is currently no way to prevent or reverse grey hair, understanding the underlying mechanisms can help us better appreciate the natural aging process. So next time you notice a few silver strands, embrace them as a badge of honour and a reminder of the beauty and complexity of the human body.

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