Scientists announced the creation of the first effective therapy for COVID-19
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The therapy uses the technology of suppressing RNA genes, which stops the replication of the virus.
Scientists have developed an experimental direct-acting antiviral therapy to treat COVID-19. About it stated at Griffith University on Tuesday, May 18.
The study was carried out by an international team of scientists from the Menzies Institute of Health in Queensland at Griffith University (Australia) and from the City of Hope Medical Center (USA).
The next generation antiviral approach used RNA gene suppression technology called miRNAs (small interfering RNAs) to directly attack the viral genome, which stops viral replication, and lipid nanoparticles developed at Griffith University and City of Hope to deliver miRNAs to the lungs – a critical focus of infection.
“Treatment with virus-specific siRNA reduces viral load by 99.9%,” the scientists said.
So far, the therapy has been tested in infected mice. The treatment improved their survival and the dynamics of recovery. In the surviving and cured mice, no virus was found in the lungs.
According to Professor Kevin Morris, the drugs are suitable for the treatment of all beta-coronaviruses like SARS (SARS-CoV-1) and SARS-CoV-2, as well as other new variants that may arise in the future, because the therapy is aimed at ultra-conserved regions of viral genomes. … Nanoparticles are stable at 4 ° C for 12 months and at room temperature for more than a month, so the agent can be used in the absence of special storage conditions.
Recall that earlier scientists discovered vulnerability genes for coronavirus… Experts warn that carriers of genetic variants SLC6A20, ERMP1, FCER1G and CA11 have a high risk of developing coronavirus infection.
It was also reported that the scientific community doubted reliability of data on the Sputnik vaccine… Epidemiologists from different countries have noticed many inconsistencies in the data presented by Russian scientists, as well as a number of unusual and suspicious coincidences.
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