Scientists at Central Oxford University develop world’s first ovarian cancer vaccine – Senator News

Beritasenator.com. Vaccination it is still in the early stages of development, but if test successful, the vaccine may help prevent both forms cancer most common for women.

Expert at Oxford University developing a cancer vaccine pride first in the world, which aims to prevent the disease which kills almost 26,000 women in European Union every year.

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The vaccine, called OvarianVax, trains the body’s immune system to recognize and fight ovarian cancer in its early stages, one of the most common types of cancer among women that often goes undiagnosed until later stages forward, when it is more difficult to handle.

The vaccine targets women with genetic mutations that may increase their risk of ovarian cancer.

Some women with this mutation choose to have their ovaries and fallopian tubes surgically removed to try to prevent cancer, even if they are unable to have children.

“We need better strategies to prevent ovarian cancer,” Dr Ahmed Ahmed, an Oxford gynecological oncologist and head of the OvarianVax project, said in a statement.

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“Teaching the immune system to recognize the early signs of cancer is a difficult challenge,” he said. “However, now we have very advanced tools, which give us real insight into how the immune system recognizes ovarian cancer.”

Ahmed’s team will try to find out how well the immune system recognizes different proteins on the surface of ovarian cancer cells, and conduct laboratory tests to measure how effectively the vaccine can kill organoids, which are miniature models of cancer grown from tumor tissue taken from patients. .

If these initial tests are successful, researchers will move forward with clinical trials to test how well the vaccine works in humans.

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The project could lead to “important discoveries in the laboratory that will fulfill our desire to improve survival for ovarian cancer,” said Michelle Mitchell, chief executive of the non-profit Cancer Research UK, in a statement.