Samcofenac: Meaning, Benefits, Dosage, and Side Effects Explained

Jakarta –

Samcofenac is a pain reliever and anti-inflammatory drug. This drug is a hard drug, so it is not sold freely. You must bring a doctor’s prescription to get this medicine.

To find out more information about Samcofenac, see the explanation below. We will review it starting from the meaning, benefits, dosage or rules of use, to side effects and contraindications.

Samcofenac What medicine?

Reporting from the official website, Samcofenac is a Nonsteroidal Anti-Inflammatory Drug (NSAID) which contains 500 mg diclofenac sodium.

In the book Preventing & Treating Various Joint Diseases: Gout, Rheumatism, and Other Joint Diseases (2021) by dr. Iskandar Junaidi, diclofenac sodium is a phenylacetic acid derivative which has analgesic, antipyretic and anti-inflammatory powers.

The way this drug works is to inhibit prostaglandin synthesis. The content will be completely absorbed from the digestive tract and peak levels in the blood are reached within 2-3 hours.

More than 90% of this drug is bound to plasma proteins, especially albumin. Then most of it is excreted in the urine and only a small part is excreted in the bile.

Benefits of Samcofenac

Samcofenac is a pain reliever and anti-inflammatory drug. This drug is commonly used for the treatment of acute and chronic symptoms of arthritis, including:

1. Rheumatoid Arthritis

This is a condition when the body’s immune system attacks the lining of the joint capsule or the hard membrane that covers all parts of the joint.

As a result, the synovial membrane layer becomes inflamed and swollen, which can destroy the cartilage and bone in the joint.

2. Osteoarthritis

A condition that occurs when joint cartilage wears and tears. This damage can cause friction between the bones, causing pain.

Ankylosing Spondylitis

This is inflammation which over time can cause some of the bones in the spine to fuse together. This can make the spine less flexible and result in a hunched posture.

Dosage and Directions for Use

The dose of Samcofenac is differentiated according to the type of pain. This dosage is written on the packaging, namely:

Osteoarthritis: 50 mg, 2-3 times daily or 75 mg, 2 times daily. Rheumatoid arthritis: 50 mg, 3-4 times daily or 75 mg, 2 times daily. Ankylosing spondylitis: 25 mg, 4 times daily, 25 mg added when going to sleep at night.

As explained on the Ministry of Health’s website, anti-pain medication has instructions for use so that it causes stomach ache when consumed.

The method is to take pain relievers after eating. In addition, do not take anti-pain medication together with alcohol.

Side Effects and Contraindications

Like most drugs, Samcofenac also has side effects and contraindications to be aware of:

Side effects

Common side effects include stomach pain or cramps, headache, fluid retention, diarrhea, nausea, flatulence, constipation, indigestion, stomach ulcers, dizziness, rash, abnormalities in liver test results, pruritis, and tinnitus. Other side effects, such as:

Increased hepatitis aminotransferase enzymes (SGOT, SGPT). In limited cases, hematological disorders occur (thrombocytopenia, leucopenia, agranulocytosis, anemia).

Contraindications

If you have a history or condition below, check its use with your doctor first:

History of allergies to NSAIDs. Have a history of stomach and intestinal disorders. Have a history of kidney problems. Pregnant and breastfeeding women should consult a doctor.

That’s how we found out what Samcofenac is. This drug is a pain reliever and anti-inflammatory that can be used for rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Hope it is useful.

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(bai/inf)

2023-11-22 05:13:14
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