RSV Causes Nerve Cell Damage – 70% Increase in Infants and Young Children

RSV causes specific nerve cell damage…Recently, RSV patients are increasing, 70% in infants and young children.

Entered 2024.02.01 16:18 Entered 2024.02.01 16:18 Modified 2024.02.01 13:21 Views 225

Research has shown that RSV, a common respiratory infection in infants and young children, can have a negative effect on nerve cells. [사진=게티이미지뱅크]Research results have shown that the recently popular ‘respiratory syncytial virus (RSV)’ can cause damage to nerve cells. RSV is a respiratory infectious disease that commonly affects infants, young children, and the elderly. It is spread through droplets through saliva, sneezing, or contact and is known to be a highly contagious virus.

Mouse nerve tissue culture experiment, damage due to inflammation

According to a recent study published in The Journal of Infectious Diseases, it was discovered that RSV can directly or indirectly affect specific cells such as peripheral nerves, British health and medical media ‘MedicalNewsToday’ said. )’ introduced. The researchers investigated the effect of RSV on the nervous system through mouse nerve tissue culture and confirmed that RSV can cause inflammation and then nerve damage.

The researchers conducted experiments by culturing rat nervous tissue, and collected and analyzed samples on the 1st, 8th, and 30th days to see if there were any changes. As a result, in the spinal cord, certain cells such as microglia and dendritic cells, a type of macrophage, were infected with RSV, but neurons were not affected. In the peripheral nerves, neurons, dendritic cells, and macrophages as well as dendritic cells were infected with RSV. Macrophages are cells involved in the body’s immunity, especially inflammatory reactions. When nerves are damaged by RSV, chemokines, proteins involved in inflammation, are released, which can cause inflammation. Dendritic cells are also cells related to the immune system that respond to antigens.

Significance of identifying potential risks, verification is necessary

This study is considered to be significant in that it confirmed the effect on the nervous system in an environment where recent RSV-related research has focused on its effect on the respiratory system. Dr. Giovanni Piedimonte of Tulane University School of Medicine, who participated in this study, said, “This study is the first to demonstrate that RSV can affect peripheral nerves, and may provide a link between neurological symptoms related to RSV.” He praised himself.

In the same context, the results of this study can explain to some extent the fact that infection with RSV increases the risk of suffering from asthma in the future. Previously, research results were published in the medical journal The Lancet, showing that being infected with RSV within the first year of life may increase the risk of developing asthma within 5 years. There was a whopping 5% difference in the likelihood of developing asthma between children who had been infected with RSV and those who had not. Asthma is a chronic respiratory disease that occurs in the bronchi connected to the lungs, with recurring symptoms such as coughing, wheezing, difficulty breathing, and stuffiness.

However, some say that there is still a long way to go to prove a clear connection between RSV and the nervous system. It is pointed out that since the experiment was conducted with human stem cells and rat nervous tissue culture, more evidence and verification in humans are needed to prove this fact. The complexity of the influencing process is also one of the challenges that must be solved.

Recent increase in patients, suspicious if breathing sounds are abnormal.

RSV mainly attacks the lungs and is known to be a particularly dangerous virus for premature babies, newborns, infants, as well as adults with weakened immune systems, the elderly, and people with chronic lung disease. It is characterized by cold-like symptoms such as a runny nose, fever, and cough, as well as a narrowing of the airways and a wheezing sound. Although it is a common disease, caution is needed as it can cause breathing difficulties in infants and, in severe cases, can lead to serious respiratory diseases such as bronchiolitis and pneumonia. If you notice any abnormal symptoms such as a runny nose or cough, as well as unusual breathing sounds or difficulty breathing, you should visit a hospital immediately.

Recently, in Korea, the number of patients is rapidly increasing as RSV becomes prevalent along with mycoplasma pneumonia, whooping cough, and COVID-19. According to the Korea Disease Control and Prevention Agency, the number of domestic patients hospitalized with RSV infection in the last week of December last year (24th to 30th) was 450, a 2.3-fold increase compared to the first week of December. Approximately 70% of the patients were infants and children aged 0 to 6 years.

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2024-02-02 13:27:57

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