12/04/2024 20:09 – UPDATED 12/04/2024 20:09
Alternative to insulin in type 1 diabetes. Close time a 100 yearsthe treatment of type 1 diabetes he did not advance at all. More exactly, to achieve insulin replacement. This, despite the fact that, “Insulin does not provide satisfactory glycemic control in most people. In this way, there remains a significant need for new treatments for type 1 diabetes,” said the doctor Colin M. Dayan, from the Diabetes and Autoimmunity Group of the Faculty of Medicine (Cardiff University, UK). We find out in the continuation of the article about what alternative it’s also about how type 1 diabetes can be detected early. (Continue reading after the photo)
Alternative to insulin in type 1 diabetes
And type of immunotherapy could help control of type 1 diabetes. Experts believe it is more of an autoimmune disease than a metabolic one. During the XXXV National Congress of the Spanish Diabetes Society (SED), Dayan defended use of low-risk immunotherapy. This, in order to preserve the endogenous function of beta cells and facilitate metabolic control. In this way, he points out, “insulin and/or beta cell replacement (stem cells or transplant) should cconsidered rescue therapies reserved for late presentations in the future”, according to abc.
For Dayan, type 1 diabetes is more of an autoimmune disease than a metabolic one. In this sense, he is “delighted with the recent approval of the drug teplizumab in order to delay insulin requirement between 2 and 3 years”. Especially since it is the beginning of a new era. In fact, “there is at leastn other 7 medicines which have beneficial effects and should be able to extend this period even more”. In his opinion, “there is no doubt that now it is possible to delay the loss of insulin-producing cells with low risk to patients. Besides, we can expand now this period of “type 1 diabetes without insulin” for much longer,” says the expert from the University of Wales. (Continue reading below)
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Conform rESULtS which become known following these studies, stands out new and revolutionary trends in the prevention of type 1 diabetes. “We have to think how it should bewe value first degree relatives of people with diabetes (who have 10 times greater risk). Then later to the general population, to detect preclinical type 1 diabetes (using auto-antibodies islet cells, ICA), before too many insulin-producing cells to get lost“, he advises. (Read more)
It is desired to control the disease much more effectively
Currently, like most other autoimmune diseases, diabetes can be controlled for many years without the need for insulinalthough it may be necessary a continuous treatment. “If we understand the stages of the disease, we can move to ‘type 1 diabetes without insulin,'” he points out. Changes in diet do not change the appearance of the disease. But when the disease is close to onset, exercise can burn sugar and delay clinical onset, but eventually diabetes will occur anyway. It is precisely because of advances in the use of immunotherapy for type 1 diabetes that Dayan believes it is essential that we start “exploring how to detect disease before too many insulin-producing cells are lost.” The expert suggests screening of first degree relatives, because they have a 10 times greater risk of contacting the disease. In the longer term, it is wanted detection of preclinical type 1 diabetes using islet autoantibodies. This situation, in his opinion, “would not lead to the cure of the disease, but, as in most other autoimmune diseases, can be controlled much bettersuch that insulin may not be needed for many years”.
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2024-04-12 18:09:00
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