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Reviving Extinct Species: Can RNA Sequencing Bring Back the Tasmanian Tiger?

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26 Sept. 2023 08:01 a.m.

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The Tasmanian tiger, or thylacine, is a striped marsupial the size of a dog. In the past, they lived on the Australian continent and nearby islands. It is an excellent hunter even though it has become extinct. But researchers haven’t stopped studying them. Recently, a research team led by geneticists from the Center for Paleontological Genetics. And Xylife Lab in Sweden said it had recovered “RNA” (RNA, or ribonucleic acid) from the dried skin and muscles of Tasmanian tigers. Stored since 1891 at the Swedish Natural History Museum. in Stockholm Researchers reveal that sequencing and analyzing old RNA It may help rebuild extinct species.

“RNA” (RNA) is the genetic material that is present in all living cells. Its structure is similar to “DNA” (DNA or deoxyribonucleic acid), the double helix molecule that contains the genetic code of living things. There are genes that give rise to all living things. while RNA is a single-stranded molecule that carries the genetic information received from DNA. and put this information into practice RNA synthesizes many of the proteins that living things need to survive. and works to control cell metabolism Researchers say RNA sequencing will reveal the metabolic controls that occurred in the cells and tissues of Tasmanian tigers before they became extinct.

As for how long RNA can survive, such as at room temperature, the remains of a Tasmanian tiger at the museum are in a semi-mummified state. Still maintaining the skin muscles and bones but without internal organs Most researchers think that RNA only lasts for a short period of time. Just a day or week at room temperature. This may be the case when the carcass is dead or damp. But that doesn’t seem to be the case when the remains are dry. Recovering RNA from old viruses could help decipher the causes of past pandemics.

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