Home » Health » Researchers have discovered the mechanism for hair turning grey, suggesting stem cells may get stuck and lose the ability to maintain hair colour, and if findings for humans are consistent, it could offer the potential to reverse or prevent grey hair. Stem cells in mice skin, melanocyte stem cells (McSCs), have the unique ability to transition between hair follicle growth compartments, losing this ability with age, according to the study from researchers at New York University Grossman school of medicine. Hair colour is controlled by McSC development into mature cells that make protein pigments for colour.

Researchers have discovered the mechanism for hair turning grey, suggesting stem cells may get stuck and lose the ability to maintain hair colour, and if findings for humans are consistent, it could offer the potential to reverse or prevent grey hair. Stem cells in mice skin, melanocyte stem cells (McSCs), have the unique ability to transition between hair follicle growth compartments, losing this ability with age, according to the study from researchers at New York University Grossman school of medicine. Hair colour is controlled by McSC development into mature cells that make protein pigments for colour.

As we age, it’s common for our hair to lose its color and turn grey or white. While some people embrace their silver strands, others may seek out ways to reverse the process. Now, scientists believe they have uncovered a genetic variation that may explain why hair turns grey, shedding light on the aging process and potentially opening the door for new treatments. In this article, we’ll explore this exciting discovery and what it could mean for the future of hair care.


Scientists have discovered a potential mechanism behind greying hair, which could help develop treatments to halt or even reverse the process. The findings suggest that stem cells in hair follicles may become fixed in place as hair ages, losing the ability to mature and maintain hair colour. Certain stem cells, which have the ability to transform into many different cell types, are able to transition between growth compartments in follicles. However, as the cells age, they lose the ability to move between compartments, leading to greyness. The research focused on melanocyte stem cells, or McSCs, which are found in the skin of mice and in humans. Scientists believe that if their findings hold true for humans, they could provide an opportunity to prevent or reverse grey hair by helping to move jammed cells between developing hair follicle compartments. 

Hair colour is controlled by the maturity of melanocytes, which make the protein pigments responsible for colour. These melanocytes are formed by continually multiplying pools of McSCs within hair follicles, which receive the signal to become mature cells. The researchers found that during normal hair growth, McSCs pivot between compartments of the developing hair follicle. Inside these compartments, signals that influence maturity are received. As hair ages, sheds and repeatedly regrows, increasing numbers of McSCs can become fixed in place within the hair follicle bulge, where they remain.

The study was led by researchers from New York University Grossman School of Medicine. The lead investigator suggested that the mechanisms uncovered could be present in humans, providing a route to reversing or preventing greying hair. However, further research is needed. The findings highlight the loss of the chameleon-like function in melanocyte stem cells as responsible for greying and loss of hair colour.


In conclusion, the discovery of why hair turns grey is a breakthrough that sheds light on the complex biological processes that occur in our bodies as we age. While the findings are fascinating, it’s important to remember that grey hair is a natural part of the aging process and not something to be ashamed of. Rather, it’s a testament to the resilience and adaptability of our bodies as we navigate the challenges and joys of life. As scientists continue to reveal the mysteries of our bodies, it’s exciting to think about what other discoveries may be just around the corner. For now, let’s celebrate the beauty and diversity of grey hair and embrace the journey of growing older with grace and dignity.

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