Researchers from the University of Pittsburgh and Italy found disrupted sleep and irregular daily routines contributed to schizophrenia spectrum disorder symptoms. The study surveyed 250 participants with SSD and measured their activity and rest throughout the day and night by asking them to wear a wristband that detects movement and acceleration. It found that both residential and outpatient SSD patients tended to have fewer active hours during the day and spent more time sleeping or passively resting than healthy controls.

Schizophrenia is a chronic mental illness that affects millions of people worldwide. It is characterized by disrupted thoughts, emotions, and behaviors. While the exact causes of schizophrenia are not yet fully understood, research has suggested that disrupted circadian rhythms may play a role in the development and maintenance of the disorder. Recently, a new study has further explored this connection by discovering that disrupted rhythms of rest contribute to schizophrenia spectrum disorder symptoms. This article will delve deeper into the findings of this study and shed light on how disrupted rhythms of rest could be a potential target for future treatments of schizophrenia.


Researchers from the University of Pittsburgh and from Italy have identified common sleep patterns and dysregulated daily rhythms across patients with schizophrenia spectrum disorder (SSD). The study conducted on 250 participants, including both residential and outpatient SSD patients, found that patients with SSD had irregular sleep patterns, disrupted transitions between sleep and wake cycles, and extremely rigid daily routines, all of which were predictive of worse SSD symptoms and correlated with lower quality of life. Residential patients demonstrated more fragmented sleep as well as abrupt transitions between rest and activity, and these patients also displayed more rigid daily rhythms. Additionally, the study found that sedative medications used to manage SSD symptoms are known to alter sleep and extend patients’ resting time up to 15 hours per day. Too much sleep can be harmful to SSD symptoms. On the other hand, researchers have suggested that regulating sleep and wake cycles can improve patients’ health and overall quality of life. The findings were published in the Molecular Psychiatry journal. The researchers admit that it is not possible to use sleep markers to diagnose SSD due to the overlap of these symptoms with other mental health conditions such as dementia. Nonetheless, it is advised that everyone should vary their daily routines and incorporate more physical activities into their lives to improve and protect their brain health as well as their quality of life.


In conclusion, the findings of this study underline the crucial role that disrupted rhythms of rest may play in the manifestation and severity of schizophrenia spectrum disorder symptoms. The disruptions can hinder the body’s natural ability to regulate its internal clock, leading to a cascade of adverse effects on mental health. By shedding light on these mechanisms, this research paves the way for more targeted interventions and holistic approaches to treat schizophrenia and improve the well-being of affected individuals. As we continue to unravel the complexities of this debilitating condition, a greater understanding and appreciation of the impact of disrupted sleep cycles will undoubtedly be an essential step towards more effective management and eventual cure.