Headline: Refeyn Launches Next-Gen Microfluidic Chips for Enhanced Mass Photometry
In a significant advancement for the bioanalytical landscape, Refeyn, a leading innovator in mass photometry technologies, has unveiled an expansion of its consumables portfolio aimed at simplifying and enhancing the efficiency of mass photometry. The introduction of next-generation microfluidic chips, improvements to its microfluidic system, and a new protein calibration standard promise to save users valuable time while ensuring reproducibility across various experiments and laboratories.
What’s New in Refeyn’s Offerings?
Refeyn’s latest product rollout includes the 2nd generation of its MassFluidix® microfluidic chip, designed specifically for rapid sample dilution and mass photometry measurements. This advanced chip boasts five channels, enabling mass photometry measurements at unprecedented speeds—taking less than 37 milliseconds for each sample dilution.
One of the key enhancements involves a redesigned channel system that eliminates the need for a bubble trap, making it more user-friendly. The new chip also features luer connectors, facilitating easy connections to tubing and eliminating the hassle of complex setups. Each chip is individually packaged, allowing customers to use them as needed, thereby increasing convenience and efficiency.
Enhanced Software Integration
Complementing the hardware advancements, Refeyn has integrated new software functionalities that streamline operations. Users can now operate the rapid dilution system directly through the AcquireMP mass photometer control software. A newly introduced automatic microfluidic chip channel detection feature simplifies measurements by ensuring that the chip is correctly positioned before each reading.
Expanding Applications and Potential
The upgraded MassFluidix system enhances the characterization of highly concentrated samples, which is essential for quality checks in demanding techniques such as cryo-electron microscopy (cryoEM) and crystallography. Furthermore, it enables scientists to explore low-affinity and transient biomolecular interactions with greater ease, a breakthrough in the understanding of complex biomolecular models.
This has significant implications in studying traditionally challenging sample types, including Protein Targeted Chimeras (PROTACs) and multi-component interplay, while also extending to more common applications like antibody-receptor binding.
New Standards for Precision
In addition to the microfluidic chips, Refeyn is introducing the MassFerence® P1 protein calibration standard—a new addition to its range of calibration standards that ensures maximum precision for mass photometry measurements. Simple to prepare, the MassFerence® range provides standardized references that enhance replicability across different experiments and instruments. This particular product is designed for use with Refeyn’s TwoMP and OneMP mass photometers, catering to proteins ranging from 90 to 1000 kDa.
Commitment to Customer Needs
Gerry Mackay, CEO of Refeyn, expressed enthusiasm about the new offerings, stating, “These new products reflect our commitment to responding to customer needs and working to provide the best possible experience for all users of mass photometry technologies. With their introduction, we aim to optimize the efficiency and quality of mass photometry experiments, making mass photometry useful for a wider range of samples.”
Camille Hetez, Director of Consumables at Refeyn, echoed this sentiment, highlighting the company’s proactive approach in tailoring products that enhance user experience: “We’ve listened to our customers and made many changes and additions to suit their requirements. By using consumables that we’ve developed specifically for Refeyn instruments, our customers can benefit from hassle-free measurements, with less time needed for sample prep and more confidence in their mass photometry biomolecular analysis results.”
Future of Bioanalytics
As Refeyn’s advancements signal a transformative moment in mass photometry, the potential benefits extend beyond the laboratory. Improved bioanalytical tools could lead to breakthroughs in drug discovery, diagnostics, and a deeper understanding of biological interactions, ultimately impacting healthcare and life sciences.
For technology enthusiasts and industry professionals alike, the new products are a welcome development in the field of bioanalytics, fostering innovation and improving research outcomes.
For more insights on advancements in technology, you can read our articles on the latest innovations in the field here.
As mass photometry continues to evolve, the implications for future research are vast. What are your thoughts on this new release from Refeyn? Share your perspectives in the comments below!
