The journey of the Corona Q677H virus mutation has apparently been discovered in May 2020. The virus code was found along with the discovery of the mutation of the Corona D614G virus.
Nyoman said, the initial discovery of the Q677H was spread in six countries, including Indonesia, to be precise in Surabaya. Currently, the Q677H virus mutation has developed in 24 countries.
“This is certainly interesting, from six countries in May 2020. Then now it has developed into 24 countries. The location of the Q677H mutation coincides with the same mutation location as D614G,” he continued.
“This means that at the location of the spike protein (which is shaped like spikes) there are two charges that are close to each other and also close to the human host cell protein. They help cut the spike into two sub units, namely Spike (S1) and Spike 2 (S2). ). “
So does the discovery of the Q677H at the same location make it similar to the transmission speed of the D614G? From laboratory test results, the D614G mutation was found to be 10 times more contagious.
“The research team is trying to block the mutation locations. Regarding which Q677H and D614G are more contagious, we cannot inform you yet,” he explained.
“Yes, because the Q677H mutation has just been discovered. So, it is necessary to further investigate the protein-protein interaction pattern between host cell proteins and viral proteins.”
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