Intracerebral hemorrhage is a terrible event that often leads to death, and the survivors recover for a long time after this tragedy. Unfortunately, most hemorrhages occur in the second stage, when blood cells lyse and form neurotoxic products, so they are more likely to be fatal.
Therefore, a team from the University of Helsinki, together with neurologists from Taiwan decided to studywhether a particular protein can penetrate the site of damage and carry out a life-saving cleansing of the brain from toxins and other debris.
The authors of the study in the Finnish laboratory.© helsinki.fi
This substance is known as cerebral dopamine neurotrophic factor (CDNF), and it is already known to many researchers as a potential cure for Parkinson’s disease. However, its miraculous “cleaner” properties were discovered for the first time. Animal experiments have shown that CDNF accelerates the resolution of hemorrhagic lesions, reduces cerebral edema, and reduces cellular stress in the area of the hematoma.
But, most surprisingly, this neutrotrophic factor increases the production of anti-inflammatory mediators and suppresses the production of pro-inflammatory cytokines, which are responsible for cellular signaling. This increases the activity of immune cells in the area of hemorrhage and, thus, the brain gets rid of dangerous toxins faster. If further research is successful, it is possible that soon CDNF will become a new drug for cerebral hemorrhages.
