SURABAYA, iNewsSurabaya.id – Prof. Girl Meinar Sari has just been confirmed as Professor (gubes) of the Faculty of Medicine, Airlangga University (FK UNAIR).
In his inauguration, Prof. Girls delivered his oration with the title Remodeling Balance through Cellular Orchestral Harmonization as a Bone Density Projection.
He said that bones are one of the most important tissues in the main structure of the human body and have a big role in human survival.
There are two most important phases in the formation of human bone structure. Namely, the coupling process between the dismantling process (resorption) which releases calcium for metabolism is carried out by osteoclast cells and the formation process (formation) by osteoblast cells. These two phases are known as bone remodeling.
One of the most important components in bone remodeling is the balance of cooperation between the constituent bone cells, namely osteoblasts, osteoclasts, osteocytes and lining cells, with the surrounding biomolecular matrix.
“It’s like an orchestra that requires harmonizing the rhythm of each musician’s work to produce good musicality. “The same goes for human bones,” said Prof. Girl.
Humans will continue to experience a remodeling process throughout their life until the age limit for bone growth or peak bone mass which occurs at the age of 30 years. Past this age, humans will experience a decrease in bone density due to an imbalance in remodeling.
Silent Killer
The professor who was born in Malang City said that this imbalance causes problems in human bones, one of which is osteoporosis. According to his presentation, menopausal women have a high susceptibility to osteoporosis.
This is caused by decreased production of estrogen which functions to maintain osteoblasts for bone formation. Furthermore, the FK Governor revealed that osteoporosis cannot be underestimated and can be a silent killer.
“Most people who experience osteoporosis are not aware of this. “Because there are no symptoms and bone damage and fracture can be detected,” he said.
This is supported by data that shows 1 in 3 women and 1 in 5 men aged over 50 years are at risk of experiencing bone fractures due to osteoporosis. This causes 50 percent of hip fractures which result in lifelong disabilities and contribute to death rates.
Preventive and promotive steps
The LPPM chairman explained that the risk of osteoporosis could be prevented by taking early preventive and promotive steps. One of them, doing submaximal physical exercise. This will stimulate the liver to produce Insulin-like Growth Factor-1 (IGF-1), which plays a role in increasing the performance of osteoblast cells.
Apart from that, physical exercise must be balanced with good food intake in the body. One of them is by consuming soybean extract which contains phytoestrogens and salmon calcitonin to suppress osteoclast activity and minimize motility and resorption capacity. Don’t forget, kenikir leaves are also an ingredient that can increase the number of osteoblasts and the biomarker C Telopeptide (CTX).
“With the hope that the innovation I present can increase public insight and awareness regarding the importance of early protection of bone density,” he said.
Editor: Ali Masduki
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2023-12-28 01:40:32
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