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Prof Zullies Review Lois Owien’s Claim About Drug Interaction

Dr Lois Owien has often made controversial statements about Covid-19.

REPUBLIKA.CO.ID, JAKARTA — Dr Lois Owien who often makes controversial statements about Covid-19 has been arrested, Sunday (12/7) afternoon. General practitioner who works anti aging it also makes a claim that corona virus is not real and Covid-19 patients die mostly as a result of drug interactions.

What exactly is a drug interaction? UGM professor of pharmacy Prof. Zullies Ikawati, PhD, Apt explained that drug interactions is the effect of one drug on the effect of another drug when used together in a patient.

“In general, this interaction can cause an increase in the pharmacological effects of other drugs (synergistic or additive), or reduce the effects of other drugs (antagonists), or increase the unwanted effects of the drugs used,” said Zullies. Among.

That way, actually this interaction does not all have a dangerous connotation. Because, there are drug interactions that are beneficial, some are detrimental.

“So it cannot be generalized, and must be studied individually,” said Zullies.

Many disease conditions require more than one drug for treatment, especially if the patient has more than one disease (comorbid). The same thing happened in the case of Covid-19 patients who had comorbidities.

Hypertension, for example, cannot be controlled with just a single drug. Sometimes, this high blood pressure disease requires other antihypertensive drugs in combination with two or three other antihypertensive drugs.

In this case, Zullies explained that the selection of drugs to be combined must be right. Each drug must have a different mechanism.

“It’s like catching a thief, he can be blocked from various directions. In this case, the drugs can be said to interact, but this interaction is a beneficial interaction, because it is synergistic in lowering blood pressure,” said Zullies.

So what about Covid-19 therapy? Zullies revealed, Covid-19 is a unique disease where the condition of one patient with another can vary greatly.

In cases of Covid-19 with moderate to severe symptoms, for example, lung inflammation, blood clotting disorders, or digestive disorders can occur. Therefore, it is very possible that several kinds of drugs are needed to treat these various disorders, in addition to antiviral drugs and vitamins.

“If you don’t get the right medication, it can actually worsen the condition and cause death,” said Zullies.

In this case, the doctor will certainly consider the benefits and risks and choose the best drug for his patient. No doctor wants his patient to die with the drugs he prescribes.

Zullies explained, drug interactions can be detrimental if the presence of a drug can reduce the effect of other drugs used together. Or it could be that if there are drugs that have the same risk of side effects as other drugs used together, it will further increase the total risk of side effects.

source: Between

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