Have you been experiencing chronic sleep loss lately? Are you also suffering from inflammation and oxidative stress? If yes, here is some great news for you. Recent research in the field of neuroscience suggests that supplementing with probiotics can help reduce inflammation and oxidative stress caused by chronic sleep loss. In this article, we will discuss the study’s findings and explore how probiotics can help alleviate these issues. So, buckle up and delve deep into this incredible discovery.
Probiotics have become increasingly popular in recent years for their antioxidant and anti-inflammatory properties, which have been shown to have a positive impact on gut flora and the body’s immune system. Now, new research suggests that probiotic supplementation may be a positive strategy to counteract the negative effects of sleep loss and benefit our physical and mental health.
Sleep is essential for physical and mental well-being, accounting for approximately one-third of a human’s lifetime. Chronic Sleep Restriction (CSR) is defined as habitual sleep durations that are less than seven hours but more than four hours a night, and it leads to a range of brain deficits, including impaired attention and learning.
The growing body of epidemiological evidence indicates that about 30% of adults and adolescents regularly experience insufficient sleep caused by professional obligations and lifestyle habits. Studies have linked CSR to low-grade inflammation and the accumulation of intracellular reactive oxygen species (ROS) and/or reactive nitrogen species (RNS), which can cause oxidative stress-related cellular damage and other health problems.
Research shows that it is unsurprising that sleep loss-associated inflammation may depend on an alteration of the gut microbiota physiology. The administration of multi-strain probiotics can improve sleep quality by reducing the Pittsburgh Sleep Quality Index (PSQI), which is commonly used to assess sleep quality.
A multidisciplinary and multicenter team tested the hypothesis that regular oral supplementation with a multi- strain probiotic formulation could reduce oxidative stress and inflammation induced by CSR. The researchers administered a mixture of several probiotic strains (SLAB51 formulation sold as Agimixx®) or a vehicle in normal sleeping mice and in mice exposed to CSR. They concluded that the SLAB51 oral administration boosted the antioxidant capacity of the brain, limiting the oxidative damage caused by loss of sleep, positively regulating gut–brain axis hormones, and reducing peripheral and brain inflammation induced by CSR.
In conclusion, probiotic supplementation can be a possible strategy to counteract oxidative stress and inflammation caused by sleep loss. As our understanding of the gut-brain-axis grows, we can expect to see more research into the impact of supplements on the microbiome, and their effects on a range of health conditions.
In conclusion, chronic sleep loss can have a negative impact on our health, increasing inflammation and oxidative stress levels in our bodies. However, the use of probiotic supplements shows promise as a method for reducing these harmful effects. Through various studies, researchers have discovered the ability of certain strains of probiotics to promote healthy sleep and alleviate the negative consequences of chronic sleep deprivation. This newfound understanding of the relationship between sleep and probiotics offers a potential solution to the detrimental effects of poor sleep on our well-being. As further research develops, it is clear that the impact of probiotic supplementation on sleep and overall health is a topic worth exploring further.
