PRF Treatment: Healing Difficult Wounds in Autoimmune Patients

Text/Health Medical Network

Ms. Chen suffers from lupus erythematosus, resulting in thoracic spinal cord lesions and paralysis of both lower limbs. Due to prolonged bed rest at home and poor care, pressure sores formed on her ankles and wound infections. Even after one month of debridement surgery, she used many expensive Bone was still visible in the wound, and it did not improve until she went to the Department of Rehabilitation, Taipei Hospital, Ministry of Health and Welfare, and tried to receive “platelet-rich fibrin (PRF)” treatment, and finally succeeded in making Ms. Chen’s bone wound heal within 10 days. After healing, Ms. Chen happily shouted amazing!

(Schematic / photoAC)

Successful treatment of PRF in autoimmune patient wounds

Director Ye Huanrui of the Rehabilitation Department said that if patients with serious wounds want to carry out rehabilitation training, it is often difficult to perform rehabilitation due to the wounds. Therefore, medical staff need to constantly remind some care items to prevent patients from being troubled by wounds that have not healed for a long time. For example, caregivers should regularly assist the patient to turn over, the patient should use assistive devices to reduce the pressure on the affected area, and the patient should be shifted correctly to reduce shear force, and pay attention to the patient’s skin moisture control, infection treatment and nutritional supplementation, such as protein, vitamins, minerals, etc. However, many patients still develop pressure sores due to various factors after they are discharged from the hospital and return home, and the wounds may even expand to the point where it is difficult to heal.

Since Ms. Chen suffers from lupus erythematosus, and the wound is deeply visible, director Ye Yuanrui said that when encountering patients with autoimmune diseases, they must continue to use drugs recommended by rheumatology and immunology doctors, but this type of patients may Just because of autoimmunity and drug effects, wound healing is more difficult. It is necessary to consider that each wound responds differently to treatment, carefully observe and try, and after evaluating the patient’s condition this time and referring to many successful cases of “platelet-rich fibrin (PRF)” in foreign countries, it is recommended to use PRF as the treatment. The treatment method, when Ms. Chen was undergoing PRF treatment, the size of the wound was gradually shrinking every day, until the 10th day, the wound was completely healed, and there has been no recurrence after one month of follow-up.

PRF treatment with less rejection still needs professional evaluation

Director Ye Yuanrui explained that in addition to the functions of blood coagulation and hemostasis, platelets also have the functions of tissue repair and regeneration. After the human body is injured, the growth factors are locally released to promote the proliferation of blood vessels and the regeneration and repair of tissues. The blood is centrifuged to remove red blood cells to obtain high-concentration platelet plasma, so there is no problem of body rejection and side effects, and the treatment method is relatively safe.

Director Ye Huanrui shared that not all wounds are suitable for PRF treatment. For example, for superficial wounds, it is difficult to choose a suitable dressing that will not absorb PRF, so it is difficult to use this treatment method. Patients with spinal injuries, or patients who are difficult and unable to perform treatment positioning, are difficult to maintain PRF on the wound, and laser or hyperbaric oxygen will be recommended for treatment. Therefore, the treatment policy still depends on the condition of the disease. The physician discusses the decision with the patient.

This article is reproduced from “Health and Medical Network》Lupus erythematosus wound with deep visible bone healed after 10 days of PRF treatment

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