Prenatal Tobacco Exposure Linked to Increased Risk of Type 2 Diabetes in Adults – Study Finds

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Adult exposure to cigarette smoke is widely recognized as a risk factor for type 2 diabetes. Previous studies have found that adult smokers are 30% to 40% more likely to develop type 2 diabetes. – sugar type 2 to develop than people who do not smoke.

However, some researchers said it is still not clear how early exposure to tobacco smoke affects the development of type 2 diabetes, and whether this link varies by age. susceptibility to type 2 diabetes.

Preliminary study results were presented at the American Heart Association’s Epidemiology and Prevention Lifestyle and Cardiometabolic Sciences Conference in March of this year. Exposure to tobacco smoke during fetal life and smoking initiation in childhood or adolescence are strongly associated with the development of type 2 diabetes in adulthood, particularly among those with diabetes, according to the UK Biobank study of almost half a million people at high genetic risk for diabetes type 2. .

In the study, researchers reviewed data from almost 500,000 adults in the UK Biobank to assess exposure to tobacco during fetal life and initiation of cigarette smoking in childhood (5-14 years) or Adolescence (15-17 years) Association with the development of type 2 diabetes. The polygenic risk score for type 2 diabetes was used to assess the potential interactive and additive effects of early exposure to tobacco and genetic susceptibility on the development of type 2 diabetes. – sugar type 2.

Participants who had a genetic predisposition to type 2 diabetes and who started smoking in childhood or adolescence had the highest risk of developing type 2 diabetes among people who exposed to tobacco before birth or started smoking in childhood or adolescence.

Compared to people who have never smoked, exposure to tobacco smoke during fetal life is associated with a 22% higher risk of developing type 2 diabetes, those who start smoking as children are twice at risk of developing type 2 diabetes, and those who start smoking. because teenagers have a greater risk 57% People who started smoking as adults had a greater risk.

People who were exposed to tobacco smoke during fetal life, who started smoking during childhood or adolescence, and who had a high genetic risk score were more likely to develop type 2 diabetes compared to non-exposed participants who smoked tobacco early in life and had a low level of genetic risk. Genetic risk score for type 2 diabetes The risk increases were 330%, 639% and 427% respectively.

Cigarette smoke contains 6,000 chemicals, hundreds of toxic substances, and dozens of substances known to be carcinogens at the first level. The author asks smokers not to underestimate the dangers of smoking indoors. Don’t underestimate it.

Article source: Prenatal exposure to tobacco increased risk of Type 2 diabetes in adults American Heart Association