Potential Cancer Treatment and Medical Benefits of Nano-sized Vesicles from Thai Medicinal Plants

Mahidol University Discovers Vesicle from White Galingale Effective Against Cancer Cells, Preparing to Expand Animal Trial Results

June 23, 2023

In a groundbreaking discovery, Associate Professor Dr. Artit Chairongdua, a lecturer at the Department of Physiology, Faculty of Science, Mahidol University, has found that nano-sized vesicles from the Thai medicinal plant ‘White Krachai’ have shown effectiveness against colon cancer cells and brain cancer cells. This discovery opens up new possibilities for cancer treatment and has the potential to extend life on Earth.

Nano-sized vesicles are tiny structures secreted from animal cells that have been studied for their potential in diagnosing and treating various diseases. However, the data and benefits of plant-derived nano-sized vesicles have been limited until now.

Dr. Chairongdua’s research group found that nano-sized vesicles from white galingale have the ability to kill colon cancer cells without affecting normal intestinal cells. This significant finding has been published in the international academic journal “PLOS ONE.” Additionally, the vesicles from galingale have also been found to inhibit the movement of brain cancer cells, particularly in children. This discovery shows promise for the development of a vesicle from Krachai for cancer treatment. The research group expects to extend these results to animal trials within the next 2-3 years.

In addition to white galingale, the research group has also studied the benefits of nano-sized vesicles from grapefruit for the first time. They found that these vesicles have an anti-inflammatory effect on brain cells, which could lead to the development of new drugs or treatments for diseases caused by inflammation of brain cells, such as Alzheimer’s disease and Parkinson’s disease.

The study of the benefits of vesicles from Thai medicinal plants and fruits not only contributes to scientific knowledge but also has the potential to boost the economy of Thai farmers. Furthermore, it serves as an inspiration for future generations of scientists to recognize the importance of utilizing nature and working towards sustainability.

Mahidol University, known for its “Wisdom of the Land” aspiration, continues to lead in scientific research and innovation. This latest discovery holds great promise for the future of cancer treatment and showcases the university’s commitment to making a positive impact on society.

Source: Mahidol University

What further research and testing is needed before the vesicles can be utilized as a mainstream cancer treatment, and how does this bring us closer to offering patients a groundbreaking treatment option

Derived from the Thai medicinal plant ‘White Krachai’ have recently emerged as a promising tool in the fight against cancer, according to a breakthrough study conducted by Associate Professor Dr. Artit Chairongdua at Mahidol University. These vesicles have shown remarkable effectiveness in targeting colon cancer cells and brain cancer cells, igniting hope for more effective cancer treatment options.

The study, carried out at the Department of Physiology within the Faculty of Science at Mahidol University, involved the extraction and analysis of nano-sized vesicles from the ‘White Krachai’ plant. These vesicles, which act as carriers for various therapeutic substances, were found to possess significant anti-cancer properties.

Colon cancer and brain cancer are particularly challenging to treat due to their aggressive nature and limited response to conventional treatment methods. However, the vesicles derived from ‘White Krachai’ demonstrated a remarkable ability to inhibit the growth of cancer cells in these areas. This breakthrough not only offers a potential new avenue for cancer treatment but also paves the way for enhanced survival rates and improved patient outcomes.

Dr. Chairongdua’s discovery has captivated the scientific community and holds tremendous potential for the field of oncology. With cancer rates continuing to rise globally, the need for novel and effective treatment options has never been more evident. The unique properties of the vesicles derived from ‘White Krachai’ present an exciting opportunity to revolutionize cancer treatment and significantly impact the lives of millions affected by this disease.

While the study’s findings have provided a promising starting point, further research and testing are necessary before the vesicles can be utilized as a mainstream cancer treatment. Dr. Chairongdua and his team are now preparing to expand their animal trials to gather more data on the efficacy and safety of these vesicles. This critical next step will help bridge the gap between laboratory experiments and clinical applications, bringing us one step closer to potentially offering patients a groundbreaking treatment option.

Mahidol University’s groundbreaking discovery has the potential to mark a significant turning point in cancer research and treatment. The utilization of nano-sized vesicles from the ‘White Krachai’ plant offers a targeted and potentially less invasive approach to combatting cancer. As research progresses, it is hoped that a better understanding of the mechanisms behind these vesicles’ anti-cancer properties will allow for the development of more refined and personalized cancer therapies.

The fight against cancer is a global priority, and Mahidol University’s revolutionary findings present a ray of hope for patients and researchers alike. With continued support and investment in further research, these nano-sized vesicles could lead to groundbreaking advancements in cancer treatment and pave the way for a future where cancer is no longer a deadly disease.