The US pharmaceutical company Modern would like to end 2025 a Vaccine against black skin cancers onto the market. Initial study results for approval on the European market are already available.
Personalized vaccine against skin cancer
The vaccine developed by Moderna is based on the same principle as the vaccine against Corona developed by Moderna and Biontech. It is a mRNA vaccineIt activates the immune system so that it can fight the body’s own cancer cells. The vaccine is primarily intended to already with skin cancer sick patients For the vaccine to be effective, it must first be personalized become.
For this purpose, a sample of the Tumors were taken. The scientists sequence using the sample to identify the genes of the tumor tissue and identify so certain Proteins, that the cancer cells produce. These proteins are used to generate the personalized mRNA vaccine.
After Vaccination produced the sick Body Defense cells, that can identify the cancer cells and kill them. The vaccination is intended to Recurrence of cancer and formation of metastases avoided The personalized vaccine therefore strengthens the specific immune response of those affected to the tumor and helps the body to help itself.
Proteins trigger a specific immune response
mRNA vaccines contain Gene segments in the form of messenger RNA (mRNA). Through vaccination, these gene segments enter the cells. Inside the cells, the mRNA is then read, as in every cell in the body, and certain Proteins are formed. This has no influence on the DNA of the cell nucleus.
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The proteins produced by the cells trigger a specific immune response The body produces antibodies. With these antibodies, the immune system can now identify and fight the body’s own cancer cells. The vaccine will immune system the right characteristicsto identify the tumor. The vaccination is intended to train the immune system and enable it to attack the tumor cells with T helper cells and antibodies.
Die Studies with the mRNA vaccine Moderna’s vaccines are already running in Germany. Hamburg take part in 1000 patients A Permit the vaccination could already 2025 be possible. Also for other cancers This form of vaccination could be possible. In Hamburg, experiments are already being carried out with mRNA vaccines for colon cancer. However, the studies on this will take several years.
With the help of mRNA vaccination can the immune system of data subjects trained The individualized vaccine gives the immune system the Possibility, to form antibodies and T helper cells that Detecting tumor cells and fight it. This is intended to prevent the recurrence or the formation of metastases in melanoma.
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