A research study conducted by scientists from the Department of Clinical Medicine at Aarhus University and the University Hospital in Denmark revealed that Parkinson’s disease is not one disease, but rather two diseases, as Parkinson’s disease can be divided into two different types that start in different places of the body for some, neurodegenerative disease begins in the intestine and spreads To the brain In other cases, disease begins in the brain and spreads to Intestine And other members.
According to a newspaper report neuroscience Although the name might suggest otherwise, Parkinson’s disease is not one disease but two diseases, that begin either in the brain or in the gut which explains why Parkinson’s patients describe widely varying symptoms, and points to personalized medicine as the way forward for people with the disease. Parkinson’s, and the results of the study are published in the Journal of Neuroscience Brain.
The researchers said in the study that with the help of advanced scanning techniques, they showed that Parkinson’s disease can be divided into two different types, they start in different places of the body for some patients, the disease begins in the intestine and spreads from there to the brain through the nerve connections for others, the disease begins in the brain And it spreads to the intestine and other organs such as the heart
He also indicates that this finding may be very important for treating Parkinson’s disease in the future, as this should depend on the patient’s disease pattern..
Parkinson’s disease is characterized by the slow deterioration of the brain due to the accumulation of alpha-synuclein, a protein that damages nerve cells that leads to the slow, rigid movements that many people associate with the disease..
In the study, researchers used CT and MRI techniques to examine people with Parkinson’s disease.People who have not yet been diagnosed but have a high risk of developing the disease are also included in the study.People diagnosed with REM sleep behavior syndrome have an increased risk of developing Parkinson’s disease..
The study showed that some patients developed damage to the dopamine system in the brain before damage to the intestine and heart occurred in other patients. The tests revealed damage to the nervous system of the intestine and heart before damage appeared in the dopamine system in the brain.
Researchers refer to the two types of Parkinson’s disease as the body first and the brain first in the body first condition. It may be particularly interesting to study the formation of bacteria in the gut known as germs..
Where it has long been proven that Parkinson’s patients have a different microbiome in the gut than healthy people, without understanding the reason for this, now that researchers have been able to determine the two types of Parkinson’s disease, risk factors and possible genetic factors that may be different for both types can be examined and the next step is Examine whether the body’s first Parkinson’s disease can be treated by treating the intestine with fecal culture or by other methods that affect the microbiome.
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