The UK government today (30 December) has approved the COVID-19 vaccine. Developed and manufactured by the University of Oxford and AstraZeneca in the UK, it follows recommendations by the UK Drug and Health Products Regulatory Agency (MHRA), which have undergone rigorous clinical testing. And analyzed by experts And concluded that The vaccine meets the required standards for safety, quality and efficacy. It is the second vaccine approved for use in the UK after the Pfizer / BioNTech
Health Minister Matt Hancock said the vaccine will begin distribution on 4 January 2021 and will accelerate distribution in the first few weeks of 2021, a statement from the UK government said. The Joint Committee on Vaccination and Immunization (JCVI) recommends accelerating the first dose of vaccination in people at risk as much as possible. Instead of using accelerated injection to complete both doses per person in a short time.
However, all vaccine recipients will receive a second dose of the vaccine no later than 12 weeks after the first dose of the vaccine. The UK National Health System (NHS) will begin making comprehensive arrangements to distribute the vaccine.
The BBC said this was a key tipping point in expanding the scope of vaccination to bring the lives of UK residents back to normal, and pointed out that the Oxford and AstraZeneca vaccines would provide additional vaccines. Significantly up This is because the vaccine is inexpensive and can be easily produced in large quantities. It also can be stored in a standard refrigerator.
Unlike the vaccine of Pfizer / BioNTech That must be stored under temperatures of -70 degrees Celsius, CNN said the Oxford and AstraZeneca vaccines can be stored in a standard refrigerator at 2-8 degrees Celsius for at least 6 months. To make it easier to transport and distribute vaccines in developing countries.
However, the vaccine is approved as a ‘two-dose’ vaccine, which previously had information that Among people who received two full doses of the vaccine at least one month apart, the vaccine was approximately 62% effective. This was followed by another full dose of the vaccine, at least a month apart, the vaccine was 90% effective, bringing the overall effectiveness of the vaccine at 70%.
But the BBC said there was not enough information available to approve half a dose of the vaccine, followed by another full dose. In addition, BBC data suggests that spacing between the first and second vaccines can improve the overall effectiveness of the vaccine.
All vaccines are currently expected to be effective against the COVID-19 virus. With new mutants
The Oxford and AstraZeneca vaccines are genetically modified by the introduction of the common cold-causing virus in chimpanzees so they cannot proliferate in humans. And there is a blueprint of the thorn protein part (spike) from virus. Once it enters the human body, this protein spike is produced to stimulate the immune system to produce antibodies. And let T-cells Which are immune cells that destroy infected cells In the future, if the immune system actually comes into contact with the COVID-19 virus, it will be able to deal with it immediately.
Data from the UK government earlier stated that The UK has reserved a total of 357 million doses of the vaccine from the manufacturer, including the Oxford and AstraZeneca vaccines that have just been ordered 100 million doses. The vaccine can be injected to approximately 50 million people, and the previously approved Pfizer vaccine has 40 million doses booked, and other manufacturers include Moderna, Novavax, Valneva, GSK. / Sanofi and Janssen at different stages of testing. So far there have been more than 600,000 people vaccinated in the UK.
Proofread: Pavika Khantisrisakul
refer:
https://www.bbc.com/news/amp/health-55280671
https://edition.cnn.com/world/live-news/coronavirus-pandemic-vaccine-updates-12-30-20/index.html
https://www.gov.uk/government/news/oxford-universityastrazeneca-vaccine-authorised-by-uk-medicines-regulator
https://www.gov.uk/government/news/uk-government-secures-additional-2-million-doses-of-moderna-covid-19-vaccine
https://www.bbc.com/news/health-55040635
Source The Standard
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