Vaksin Johnson and Johnson (J&J) will come to Indonesia next month. As is known, the COVID-19 vaccine is only given in one dose.
Quoted from Al Jazeera, the company Johnson & Johnson said a vaccine booster was being considered. From the results of an interim study or initial analysis, the booster for the COVID-19 vaccine given was able to significantly increase antibodies.
A booster dose of the Johnson and Johnson vaccine, meaning the second dose of the vaccine, delivered at least nine times higher antibodies within 28 days of receiving the first dose, the companies said in their release.
Unlike neutralizing antibodies which destroy the virus, binding antibodies attach to the virus but do not destroy it or prevent infection. They alert the immune system so that the white blood cells get a signal to destroy the virus.
J&J vaccine antibodies ‘stable’ in eight months
According to J&J, the study showed a significant improvement in antibody response in participants aged 18-55 years and in those aged 65 years and over who received a lower booster dose.
Study summaries are being sent to the MedRxiv preprint server prior to peer review.
A Johnson & Johnson vaccine spokesman said the results would be available in the coming weeks. Last July, Johnson & Johnson released data in the New England Journal of Medicine showing the neutralizing antibodies produced by its vaccine remained stable eight months after a single dose of vaccination.
“With these new data, we also see that booster doses of the Johnson & Johnson COVID-19 vaccine further enhance antibody responses among study participants who have previously received our vaccine,” Mathai Mammen, head of research and development at J&J’s Janssen pharmaceutical division, said in a statement. a statement.
“We look forward to discussing with public health officials about potential strategies for our Johnson & Johnson COVID-19 vaccine, increasing eight months or more after the main single-dose vaccination.”
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