A study found that being obese in your teens or 20s increases your risk of dying from prostate cancer by nearly a third.
A large study showed that being overweight between the ages of 17 and 29 significantly increases the risk of developing, and dying from, an aggressive form of the disease.
Obesity leads to higher concentrations of insulin-like growth factor-1 (IGF-1), a hormone involved in cell growth and development, which scientists believe can cause disease.
While people cannot change risk factors such as age and family history, experts suggest that this shows that maintaining a healthy weight is something men can control to reduce their chances of developing prostate cancer.
Although many prostate cancers grow slowly and may not cause any harm during a person’s life, others are more aggressive, spread quickly outside the prostate and are difficult to treat.
The scientists wanted to examine whether obesity was a risk factor for different strains of the disease.
The researchers analyzed data on 258,477 men in Sweden who were weighed at least three times between the ages of 17 and 60, from 1963 to 2019.
During that time, 23,348 participants were diagnosed with prostate cancer and 4,790 men died, with an average age of 70 at diagnosis, according to the findings, which were presented at the European Congress on Obesity.
They found that weight gain was greater early in life among the study group, averaging 1.6 pounds per year at ages 17 to 29, 0.75 pounds at ages 30 to 44 and 0.5 pounds between ages 45 to 60.
Dr Marisa da Silva, from Lund University, Sweden, said the findings suggest that preventing weight gain in youth may reduce the risk of aggressive and potentially fatal prostate cancer.
Simon Greveson, assistant director of research at Prostate Cancer UK, said: “Many studies have indicated a possible link between being overweight and aggressive prostate cancer, and this study builds on those by suggesting that being overweight early in life is associated with an increased risk of death. “While these findings are intriguing, more research is needed to fully understand the biological link between obesity and prostate cancer – and, most importantly, how we can use this information to improve outcomes for men.”
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2023-05-19 12:36:48
#warning #men #risk #prostate #cancer
